The ingredients in Adipril appear to be identical to those in another diet pill, LipoFuze. They are also similar to those in the controversial diet pill, Apidexin. Thus, Adipril could be a blatant counterfeit or the same diet pill as LipoFuze being sold under a different name. The manufacturer of Adipril claims that the diet pill can deliver weight loss of 10 pounds in the first 7 days of use. To lose 1.5 pounds of fat per day, the body needs to burn 5000 calories above normal calorie usage. This represents a tripling in calorie burn. Adipril claims to achieve this by accelerating metabolism – but is it possible to triple metabolic rate using a pill? Highly unlikely. The medicinal herbs and other natural ingredients that are typically found in weight loss products need to be present in potent enough dosages to have any effect. As the proportion of each ingredient in Adipril is not disclosed, it is difficult to assess if they are present in the required dosages to promote significant weight loss.

Adipril side effects

You must be 18 years or older to order Adipril. The ingredients in the Adipril formulation are not harmful in themselves. However, the effect of interaction between the various ingredients has not been clinically evaluated. Internet reviews indicate that some users have reported headaches, stomachache, nausea, insomnia, profuse sweating, cramps and increased heart rate. Adipril contains caffeine but of more concern is synephrine, which has effects similar to those of amphetamines and decongestants. In some individuals, stimulants such as these can cause side effects such as palpitations and increased blood pressure.

Is Adipril effective?

User feedback on Adipril has varied. Some users have reported fast weight loss in the first few days (water loss?), but the rate of body fat loss is lower than claimed by the manufacturer.

Adipril pros

Some Adipril’s ingredients have been evaluated in clinical trials and are believed to be safe
The company does not endorse automatic enrollment programs
The official product website offers a money-back guarantee

Adipril cons

Adipril is relatively expensive for one month’s supply
The Adipril formulation does not contain any strong appetite suppressing ingredients like Hoodia or Caralluma
Adipril is a propriety blend. Are there high enough doses of the active ingredients for optimal weight loss effectiveness?
No details of the manufacturer, the country where Adipril is made or a contact address are given on the website – a red flag

Adipril ingredients

Adipril is a fat burner which contains 6 patented and 4 clinically evaluated ingredients. The ingredients include:

Bioperine: This ingredient is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). Bioperine contains 95 percent piperine. Bioperine has been shown in clinical research to increase the absorption of ingredients in nutritional supplement formulations. It is possible that the use of Bioperine may increase the side effects of certain supplements due to increased absorption.

Capsaicin: This compound is found in Chile peppers. It is believed that capsaicin generates heat in the body thereby boosting the burning of calories. However, it appears that very high doses are required for it to be effective.

ForsLean: ForsLean is derived from the root of Coleaus forskohlii. This plant is native to warm temperate habitats, including India, and is the only known plant source of the natural compound forskolin. Amongst other effects, this compound is believed to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have shown that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.

FucoPure: This compound is the patented version of fucoxanthin, a seaweed extract. There are a number of studies that have demonstrated fucoxanthin’s ability to boost metabolism, but to date, they have all been carried out exclusively in studies on animals. It is also been shown that fucoxanthin cannot be easily be absorbed by the human body. In addition, it has been demonstrated clinically that compounds like fucoxanthin have low bioavailability in man (see Br J Nutr. 2008; 100 (2): 273-277).

Green tea: Green tea can promote some weight loss. However, it needs to be used in relatively high concentration, and to contain high levels of catechins. In Adipril, the amount of green tea present in the formulation is not revealed.

GuggulEZ100: This ingredient is a patented extract of Commiphora mukul. Other common names are Gugalipids and Guggul. In India Guggul is taken to help reduce blood cholesterol. Guggul can lower cholesterol and triglyceride levels. It can help maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. There is some clinical evidence to suggest that Guggul may promote fat burning (see J Postgrad Med. 1995; 41(1): 5-7) by stimulating the secretion of thyroid T3 hormone.

Razberi-K: Also known as raspberry ketone, this compound is thought to enhance weight loss by stimulating norepinephrine. Razberi-K is claimed to aid fat oxidation, but clinical studies have not convincingly demonstrated its effectiveness. One study performed on rodents showed that raspberry ketones prevented fat synthesis as well as a rise of blood triglycerides and considered overall, helped prevent excess weight gain.

Synephrine HCL: Synephrine is derived from the Citrus aurantium. This plant used for a variety of disease indications in traditional Chinese medicine. Research indicates that Citrus aurantium can act as an effective stimulant. After Ephedra was banned by the F.D.A., diet pill makers sought to find an equivalent compound. They thought they had found it with Synephrine. However, while Synephrine is effective, there is no research that points to Ephedra and Synephrine being comparable. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium promotes a relatively modest increase in thermogenesis.

ThermoDiamine: This ingredient is the patented form of evodiamine, a Chinese fruit that is claimed to burn fat by increasing the body’s production of heat and reducing the body’s ability to store fat. However, no clinical studies have been carried out in man so far. To date only an animal-based study has been conducted and there is no clinical data on whether or not evodiamine is effective in human subjects.

7-OXO DHEA: This compound is a metabolite of DHEA, a steroid hormone. 7-OXO DHEA has been shown to have a positive effect on thyroid hormone levels in obese subjects, without apparent side effects (see J Nutr Biochem. 2007; 18: 629-634. Current Therapeutics. 200; 7: 435-442).

Conclusion

The manufacturers of Adipril are open about its composition, so that it is possible to research the ingredients beyond the information provided on the website. However, the quantities of the ingredients contained in this formulation are not listed on the official website. It is therefore impossible to evaluate if there are enough of any of the ingredients to be effective as a weight loss supplement at the recommended daily dose.

Manufacturers’ contact details

Website: http://www.adipril.com
Telephone: 1.877.778.8466