SlimVox, is a diet pill that has been formulated to promote weight loss, increase breast size, treat adult acne and boost libido. Due to its caffeine content Slimvox could cause headaches, jitters, nervousness, irritability, insomnia, nausea or headaches in individuals who react negatively to stimulants.

See also: SlimVox Review

SlimVox side effects

Due to its caffeine content Slimvox could cause headaches, jitteriness, nervousness, irritability, insomnia, nausea or headaches in individuals who react negatively to stimulants. The manufacturer recommends that a physician is contacted before starting SlimVox. This product is not recommended for women who are pregnant or nursing. To determine if SlimVox is safe to use with any other drugs or medications, it is best to consult with a physician.

SlimVox pros

• Slimvox contains all natural ingredients
• Numerous positive SlimVox reviews have been posted

SlimVox cons

• SlimVox contains caffeine
• Some users report experiencing side effects using SlimVox
• No details of the country where SlimVox is made or product quality control and purity are given on the website
• The FAQ section on the website is limited

SlimVox Ingredients

SlimVox contains the following ingredients:

Green Tea, Soy Isoflavones, Chocamine, Cinnamon, Ginger Root, Kelp, L-Tyrosine, Donq Quai , Damiana Leaves, Wild Yam Root, Oatstraw, Motherswort, Blessed Thistle, Fennel Seed, Fenugreek Seed, Magnolia Bark 4:1, Elderberry 4:1, Passion Flower and Razberi K.

Looking at the ingredients in greater detail:

Chocamine: A proprietary extract of the cocoa plant. It contains numerous constituents including methylxanthines (theobromine, caffeine, and theophylline), biogenic amines (phenylethylamine and tyramine) amino acids (phenylalanine, tryptophan, tyrosine, others), minerals, numerous beneficial antioxidants, and possibly some non-psychoactive cannabanoid-related compounds. Chocamine produces a very smooth energy boost with no crash. This ingredient is not new to fat burners but does not actually promote weight loss. Chocamine contains caffeine, which can cause side effects (see above).

Cinnamon: Cinnamon bark (Cinnamomum verum, C. zeylanicum, C. cassica) is harvested from a variety of evergreen tree that is native to Sri Lanka and India. The use of cinnamon dates back thousands of years to at least 2700 B.C. Chinese herbals from that time mentioned it as a treatment for fever, diarrhea, and menstrual problems. Indian Ayurvedic healers used it in a similar manner. Modern herbalists prescribe cinnamon bark as a remedy for nausea, vomiting, diarrhea, and indigestion. Chinese herbalists recommend it for asthma brought on by cold, some digestive problems, backache, and menstrual problems. Cinnamon bark is also known to control blood sugar levels in diabetics. Cinnamon bark may cause an allergic reaction in some individuals. It is not recommended for pregnant or nursing women. Mild side effects include stomach upset, sweating, and diarrhea. Large doses can cause changes in breathing, dilation of blood vessels, sleepiness, depression, or convulsions. Excessive use of cinnamon bark may cause red, tender gums; mouth ulcers; inflamed taste buds; and a severe burning sensation in the mouth.

Damiana: A herb which has been used as a general tonic for both men and women, particularly when hormone-related conditions are present. Damiana also has antidepressant, anti-anxiety, diuretic and mild laxative effects. It is relatively safe in regular doses, although the long term effects have not been evaluated. Damiana does have a traditional background as an abortive and therefore should not be taken during pregnancy. Damiana also has a mild hypoglycemic effect so people on diabetes medication or those who suffer from hypoglycemia must use caution with this supplement. Damiana may interfere with the body’s absorption of iron, so iron levels must be monitored while on this herb. The safety of this supplement in children has not been tested and it should not be used.

Dong quai: This phytoestrogenic herb is used in short-term treatments for alleviating menopausal symptoms, especially menstrual disorders and PMS. Unfortunately, medical research has shown that the phytoestrogens in Dong quai may accelerate the spread of breast cancer cells. Dong quai can cause skin inflammation and rashes because it increases sensitivity to sunlight. Dong quai should not be taken by pregnant women or patients being treated with any anticoagulant.

Elderberry extract: Elderberry extract is rich in anthocyanins and antioxidants which have been shown to improve health and help fight oxidative stress in the body. There are no recognized adverse effects, although data is limited. It is suggested that a diuretic of elderberry extract may result in hypokalemia, but this has not been scientifically studied. There are no recognized drug interactions in taking elderberry extract. The stems, roots, unripe berries, and seeds may contain cyanide, and could cause vomiting and severe diarrhea if chewed or eaten uncooked. Ripe berries are safe when prepared for use in foods.

Ginger root: Ginger (Zingiber officinale) contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Side effects associated with ginger are rare, but if taken in excessive doses the herb may cause mild heartburn, diarrhea and irritation of the mouth.

Green tea: Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Soy isoflavones: These isoflavones have been used to imitate and mimic the actions of estrogen. Although isoflavones are believed to be healthy, when they are taken in high doses, in food or dietary supplements, they can cause hormone levels in the body to become unbalanced. In men, this can lead to reduced testosterone levels, reduced sex drive and fatigue. In women, side effects can be more pronounced, and may include mood swings, hot flashes and weight gain.

Kelp: Because it is an excellent source of iodine, sea kelp can improve thyroid function, potentially increasing metabolism and energy and decreasing weight gain. The iodine, calcium and other minerals in sea kelp are readily absorbed by the body, assisting digestion and correcting relevant mineral deficiencies. One gram of seaweed has several times the amount of iodine that most adults require on a daily basis. Therefore, a potential kelp side effect at high dose could include changes in thyroid function due to iodine excess.

L-tyrosine: L-tyrosine is an amino acid that plays an important role in metabolism. It is the precursor to stimulatory neurotransmitters such as epinephrine, norepinephrine, dopamine and some of the thyroid hormones. All of these neurotransmitters and hormones play important roles in maintaining metabolic rate.

Magnolia bark: Used as a general anti-stress and anti-anxiety agent. Magnolia’s anti-stress benefits appear to be linked with the control of the stress hormone, cortisol. Elevated levels of cortisol have been associated with obesity, diabetes, osteoporosis, memory problems and suppressed immune function. No significant toxicity or adverse effects have been associated with the traditional use of magnolia bark. However, high doses can cause drowsiness.

Razberi-K: This ingredient, also known as raspberry ketone or 4-(4-hydroxyphenyl) butan-2-one, is believed to promote weight loss by stimulating norepinephrine. Razberi-K is claimed to aid fat oxidation, but clinical studies have not convincingly demonstrated its effectiveness. One study undertaken on rodents showed that raspberry ketones blocked fat synthesis as well as an increase in blood triglycerides and helped to prevent excess weight gain. No side effects related to raspberry ketone consumption have been reported.

Wild yam root: A plant that contains diosgenin, which can be modified in the laboratory into various steroids, such as estrogen and dehydroepiandrosterone (DHEA). Wild yam is often promoted as a natural alterative to estrogen therapy. It used to treat vaginal dryness in older women, PMS (premenstrual syndrome), menstrual cramps, osteoporosis, and reduced energy and sexual drive in men and women.

SlimVox dosage

The manufacturer recommends taking 1 capsule 30 minutes before breakfast, lunch and/or exercise with 16 ounces of water. Do not exceed 4 capsules daily. Each bottle of SlimVox contains 90 capsules and lasts 30 days when used as directed.

Force Factor Ramp Up has a relatively high content of the stimulant caffeine. Side effects reported by some users include: lightheadedness, headache, stomach ache, nausea, jitters and insomnia.

See also: Force Factor Ramp Up Review

Force Factor Ramp Up pros

• The effectiveness of Force Factor Ramp Up is supported by some positive testimonials on the internet
• Force Factor Ramp Up is backed by a 30 day money back guarantee

Force Factor Ramp Up cons

• Force Factor Ramp Up reviews are mixed with some users reporting no fat loss or muscle gain
• Force Factor Ramp Up contains relatively high levels of caffeine
• Some users report side effects using Force Factor Ramp Up
• Some customers have complained that they have been signed up for repeat subscriptions without their authorisation

Force Factor Ramp Up ingredients

Green tea extract (120 mg, standardized to 45% EGCG): Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins, which is the case in Force Factor Ramp Up formulation. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

White willow bark 100 mg, 15% salicin): White willow was used in ECA (ephedra/caffeine/aspirin) fat burners, although there is limited evidence that it enhanced this stack in any way. In non-ephedra fat burners such as Force Factor Ramp Up, it is unlikely to have any value, except as an anti-inflammatory, a fever reducer, an analgesic, an anti-rheumatic and an astringent. There are some possible side effects due to the active ingredient salicin. This is known to cause ulcers, and overdoses will lead to side effects such as skin rash, nausea, vomiting, tinnitus and kidney inflammation. Individuals with a known allergy to asprin or have blood clotting issues should avoid white willow bark.

Caffeine (100 mg from guarana and caffeine anhydrous): This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, headaches, diarrhea, insomnia and increased heart rate.

Alpha-Ketoglutaric Acid (50mg): Some individuals take alpha-ketoglutarate to improve peak athletic performance. Manufacturers of athletic nutritional supplements claim alpha-ketoglutaric acid is an important addition to diet and training for athletes seeking peak performance. Alpha-ketoglutarate appears to be safe for most adults. However, not enough is known about the use of alpha-ketoglutarate during pregnancy and breast-feeding, and it is therefore advisable to avoid use.

Marie Coral Calcium (50 mg): A form of calcium claimed to offer additional health benefits, none of which have been substantiated. Many people using calcium supplements do not have serious side effects. However, a doctor should be contacted immediately if any of these unlikely but serious side effects occur: nausea/vomiting, loss of appetite, unusual weight loss, mental/mood changes, bone/muscle pain, headache, increased thirst/urination, weakness, unusual tiredness. In addition, a doctor should be informed if any of the following medicines are taken: digoxin, cellulose sodium phosphate or certain phosphate binders (e.g. calcium acetate). Calcium can decrease the absorption of other drugs such as bisphosphonates (e.g. alendronate), tetracycline antibiotics (e.g. doxycycline and minocycline), estramustine, levothyroxine and quinolone antibiotics (e.g. ciprofloxacin and levofloxacin).

Proprietary Herbal Blend (80 mg): This blend appears to serve more as window dressing. With a mere 80 mg divided up between 6 ingredients – cayenne, bladderwrack, yerba mate, meadowsweet, wintergreen and mustard – it would appear that none of these ingredients are present in high enough doses to elicit significant side effects.

Force Factor Ramp Up dosage

The manufacturer recommends taking 1-2 capsules in the morning and 1-2 capsules in the afternoon with a large glass of water. There are 60 capsules per container.

hCG Activator is a diet pill claimed to boost is human chorionic gonadotropin (hCG). hCG can have side effects.

See also: hCG Activator Review

hCG Activator pros

• hCG Activator is manufactured to high standards in the US
• A diet protocol is included with the product
• hCG Activator comes with a guarantee

hCG Activator cons

• None of the ingredients are likely to significantly boost hCG levels
• Most clinical studies indicate that hCG does not promote weight loss
• There are side effects associated with hCG

hCG side effects

Side effects reported from taking hCG drops or receiving hCG injections include light headedness, headaches, trouble sleeping, tiredness, joint pain, muscle aches, leg cramps, hair loss and dry skin. If hCG is used for too long and in too high a dose by men, the resulting rise in natural testosterone will eventually inhibit its own production via negative feedback on the hypothalamus and pituitary gland.

hCG Activator ingredients

The hCG Activator formulation contains human chorionic gonadotropin glycopeptide stimulating complex (758 mg) which consists of L-arginine, N-acetyl L-carnitine, L-ornithine, green tea leaf extract, saffron extract, black cohosh and huperzine. Other ingredients are gelatine, cellulose, silica and magnesium stearate.

Looking at the ingredients in greater detail:

L-arginine: An antioxidant which is soluble in water and fat. L-arginine has been linked to enhanced immunity, the release of the human growth hormone, greater muscle mass, rapid healing from injury, increased sexual potency and helping to reverse atherosclerosis. However, there is no evidence that L-arginine can boost hCG levels. There can be some circulatory side effects associated with L-arginine. Individuals recovering from heart attacks should not take this compound. There is a risk of excessive bleeding because L-arginine dilates blood vessels. Hemophiliacs and people on blood thinners should probably avoid L-arginine. Sometimes L-arginine can make problems of low blood pressure more severe. In addition, individuals with sickle cell disease may find that their symptoms get worse after taking L-arginine. One of the most severe potential side effects of L-arginine is anaphylaxis - a very severe allergic reaction that can result in shock and potentially even death. In an anaphylactic reaction sudden chills, sweating, tremors, hives, vomiting, diarrhea, shortness of breath and light-headedness or fainting may be experienced. If you have any allergies, do not take L-arginine before being tested for allergy to it.

N-acetyl L-carnitine: This ingredient is an amino acid that is associated with energy production from fat stores in the body. It may help reduce symptoms of angina, diabetic neuropathy and memory impairment. However, there are no studies to indicate that N-acetyl L-carnitine has a direct effect on weight loss. Potential side effects of N-acetyl L-carnitine include stomach discomfort and insomnia.

L-Ornithine: L-ornithine is a non-essential amino acid that it is abundant in protein foods such as meat, fish, dairy and eggs. It can induce the release of growth hormone (HGH) in the body, which in turn help promote fat metabolism. There appears to be no link between L - ornithine and weight loss or HCG production. L-Ornithine can cause more frequent recurrences of herpes outbreaks. In addition, there is a link between psychotic episodes and an increased intake of L-Ornithine. This amino acid may also accentuate the adverse effects of diabetes. The use of L-Ornithine can also cause increased gastrointestinal distress. When this amino acid stimulates increased production of HGH the side effects might include excessive facial bone growth and malformation, joint swelling and pituitary gland malfunction.

Green tea: Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins. In Adipril, the amount of green tea present in the formulation is not indicated. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Saffron: This is a spice commonly used in cooking. In a recent clinical study (Nutrition Research. 2010; 30(5):305-313)) saffron was evaluated as a satiety enhancer. After 2 months, the participants using the saffron extract reported a decline in snacking and lost significantly more weight than the control group. Saffron seems safe for most individuals when used as a medicine for up to six weeks. Some possible side effects include dry mouth, anxiety, dizziness, drowsiness, nausea, change in appetite and headache. Allergic reactions can occur in some people. Ingesting large amounts of saffron is not safe. High doses can cause: a yellow appearance of the skin, eyes, and mucous membranes; vomiting; dizziness; bloody diarrhea; bleeding from the nose, lips, and eyelids; numbness; and other serious side effects. Doses of 12-20 grams can be fatal. Pregnant women should not take saffron in amounts larger than those normally found in food. Larger amounts of saffron can make the uterus contract and might cause a miscarriage. Not enough is known about the safety of saffron during breast-feeding and thus the compound should be avoided. Saffron can affect mood. There is a concern that it might trigger excitability and impulsive behavior (mania) in individuals with bipolar disorder. People who are allergic to certain plants might also be allergic to saffron.

Black cohosh: This herb has been traditionally used to treat menopausal symptoms, as a diuretic and for the treatment of infertility, painful menstruation, gynecological conditions and painful labor. Reported side effects of black cohosh include weight gain in addition to headaches and stomach discomfort. Weight gain, in fact, is listed as a common side effect in clinical trials that followed patients who took black cohosh for up to six months. Weight loss is not a reported side effect of black cohosh therapy.

Huperzine A 1% (Huperzia serrata): This is an alkaloid isolated from a Chinese moss (Huperzia serrata) that has neuroprotective and cognitive effects. Huperzine A seems to be safe when used for a short time, such as less than one month. However, it can cause some side effects including nausea, diarrhea, vomiting, sweating, blurred vision, slurred speech, restlessness, loss of appetite, contraction and twitching of muscle fibers, cramping, increased saliva and urine, incontinence, high blood pressure, and bradycardia. Not enough is known about the use of huperzine A during pregnancy and breast-feeding and therefore the compound should be avoided. Huperzine A can slow the heart rate. Since huperzine A seems to affect brain chemicals, there is concern that it might make epilepsy worse. There is concern that using huperzine A might make GI tract blockage worse. That is because huperzine A can increase mucous and fluid secretions in the intestine, causing “congestion.” The use of huperzine A might also make peptic ulcers asthma, emphysema and blockage of the urinary or reproductive system worse. Some of the anticholinergic drugs can interact with huperzine A decreasing the effects of these drying medications. Drugs for Alzheimer's disease also interact with huperzine A and might increase the effects and side effects of these medications.

hCG Activator dosage

The serving size is 2 capsules. There are 120 capsules per container.

Dieters Cheating Caps can cause possible side effects. Individuals who have allergic reactions to crabs, shrimps and related seafood should avoid this diet pill because Chitosan is an ingredient extracted from crustaceans. It is also possible to experience muscle cramps due to indigestion and water retention (feeling bloated) after taking Dieters Cheating Caps. Uncontrolled bowel movement and diarrhea is also a possibility due to the fact that less fat is digested and remains in the digestive tract. Glucomannan can become a choking hazard if not consumed with plenty of water.

See also: Dieters Cheating Caps Review

Dieters Cheating Caps pros

• There is a money back guarantee

Dieters Cheating Caps cons

• There are medical concerns about the long-term use of fat absorbers and appetite suppressants due to their potential negative impact on healthy nutrition
• The manufacturer of Dieters Cheating Caps does not promote a healthy diet and exercise as part of a weight loss program
• Chitosan is not suitable for individuals suffering from shellfish allergies
• Dieters Cheating Caps are not the only diet pill that contains glucomannan and white kidney bean extract
• There is a small number of customer testimonials on the Dieters Cheating Caps website and no before and after photos
• No details are provided on the official website concerning the name of the manufacturer, a contact address or details of where Dieters Cheating Caps are manufactured – always a red flag

Dieters Cheating Caps ingredients

Dieters Cheating Caps contains three ingredients, glucomannan, chitosan and white kidney bean extract. Looking at the ingredients in greater detail:

Chitosan (750 mg): This is a sugar that is extracted from the hard outer skeleton of shellfish, including crab, lobster, and shrimp. Chitosan is used to treat high cholesterol and Crohn’s disease. Clinical studies have shown that Chitosan has no positive effects on weight loss (see Int J Obes Relat Metab Disord. 2004;28(9):1149-1156, Singapore Med J. 2001;42(1):6-102, J Am Coll Nutr. 2006;25(5):389-394). There is significant evidence that long-term use of high-dose chitosan supplementation can result in malabsorption of some key vitamins and minerals including calcium , magnesium , selenium , and vitamins A , D , E , and K . This could lead to a risk of osteoporosis in adults and growth retardation in children. Another possible risk of taking high doses of chitosan long-term is that it could change the intestinal flora and allow the growth of health threatening bacteria. There has been a case report of arsenic poisoning caused by long-term use of chitosan supplements. Shellfish can concentrate arsenic in their shells and this may lead to chitosan supplements with an arsenic content. Pregnant or nursing women and young children should probably avoid chitosan altogether. Possible side effects may include headaches, swollen heels and wrists, breathing problems or tightness of the chest or throat, as well as chest pain and skin hives, rash, or itchy or swollen skin. There is also concern that people with allergies to shellfish might also be allergic to chitosan. In addition, there is some concern that taking chitosan might increase the blood thinning effects of warfarin (Coumadin). Taking chitosan in combination with warfarin (Coumadin) could increase the chance of bruising or bleeding.

Phaseolus vulgaris (white kidney bean extract) (750 mg): This ingredient is known to have numerous benefits particularly the ability to block starches. It can achieve this by blocking the alpha-amylase enzyme. This has the effect of preventing carbohydrates from being converted into fat – instead, they are removed from the body before they enter the blood stream. Since it prevents the proper digestion of carbohydrates, white kidney bean extract can cause several gastrointestinal side effects, including heartburn, excessive gas and diarrhea.

Glucomannan (750 mg): This is a soluble fiber. Studies have shown that glucomannan can promote weight loss by absorbing dietary fats. Glucomannan can cause side effects that include gas, bloating, nausea, stomach pain and diarrhea. Glucomannan also has the potential to bind with and reduce the absorption of certain nutrients. Glucomannan may interfere with blood sugar control. Monitor blood sugar closely if you have diabetes and use glucomannan.

Dieters Cheating Caps dosage

Serving size is 3 capsules per day. A container of Dieters Cheating Caps contains 30 capsules.

The modern fast paced lifestyle often leads to unhealthy eating habits with minimal if any real exercise. This frequently results in unwanted weight gain. To counter this problem many people try diet pills. Diet pills have different mechanisms of action – single or multiple.

Fat Burners: Many diet pills are formulated to boost fat burning in the body. They often achieve this by elevating the metabolic rate. Unfortunately they generally come with side effects.

Appetite Suppressants: These pills suppress appetite so that less food is eaten. If the body is deprived of nutrition it has to utilize its fat stores to provide energy and this promotes weight loss.

Fat and Carbohydrate Blockers: Some diet pills incorporate special types of fibers and other ingredients that can either directly absorb or inhibit the absorption of dietary fats and/or carbohydrates.

Prescription Weight Loss Pills

Obesity generally requires long-term treatment to promote and sustain weight reduction. Use of prescription drugs may be appropriate for some people. While most side effects of prescription weight loss drugs are mild, serious complications have been reported. The use of these weight loss drugs should be combined with exercise and improved diet in order to lose and maintain weight loss successfully over the long term.

Types of Prescription Weight Loss Drugs

At present, most weight loss drugs approved by the FDA are for short-term use over a few weeks or months.

Appetite suppressants can be obtained by a doctor’s prescription or purchased over the counter. One common prescription appetite suppressant is phentermine. Another type of popular prescription weight loss drug is the fat absorption inhibitor Xenical. This drug works by blocking about 30% of dietary fat from being absorbed. A reduced dosage form of Xenical, called Alli, is now sold over-the-counter. Xenical is the only weight loss drug approved for longer-term use in significantly obese people. However, its safety and efficacy have not been established beyond two years. Unfortunately, unpleasant gastrointestinal side effects are associated with  this drug.

In general, Xenical is moderately effective, leading to an average weight loss of 13 pounds or so over a one-year period. Most of the weight loss is generally seen in the first 6 months.
Over the short term, weight loss from prescription drugs may reduce a number of health risks in obese people. However, there are currently no studies to determine the effects of these medications over the long term.

Non-Prescription Weight Loss Pills

After the FDA banned amphetamines as appetite suppressants, diet pill manufacturers started producing pills containing caffeine, ephedrine and phenyl-propanolamine. When combined together, these three compounds can act in a similar manner to amphetamines. In 1982, the FDA banned the triple combination of these substances as well. More recent appetite suppressant formulations included the combination of fenfluramine and phentermine (Fen Phen) and ephedrine (Ephedra). In 1997, the Mayo Clinic reported that Fen Phen had caused heart valve disease in 24 people, initiating lawsuits and widespread media coverage. The FDA has now also banned Ephedra.

There is now a bewildering array of weight loss products on the market. Most are not particularly effective, can have unpleasant side effects and are manufactured by companies with dubious track records.

What to Look for in a Diet Pill

In tracking down a safe and effective diet pill the following are essential:

• A quality website where the manufacturer provides contact details including a full mailing address
• A full list of ingredients, preferably with concentrations
• Clinical trial weight loss data on the diet pill itself or the key ingredients
• Convincing evidence of no significant adverse side effects

Best Non-Prescription Diet Pills

Below is a selection of leading diet pills with strong positive reviews:

Proactol: Proactol is a fat binder made from the Mexican cactus plant (Opuntia Fiscus-Indica). The fiber complex consists of a non-soluble fiber and a soluble fiber that both work in different ways. Proactol is clinically proven to bind dietary fat, reduce calorie intake from fat and suppress appetite. It has also been shown to reduce blood cholesterol levels. Proactol is the first natural diet pill to be approved by the United Kingdom MHRA (Medicines and Healthcare products Regulatory Agency). This is one of the strictest medical regulatory agencies in the world, and Proactol bears their CE stamp of approval. In line with the clinical studies, many users of Proactol have been reporting appreciable weight loss with no side effects. The only side effects recorded to date are mild changes in stool consistency.

Zotrim: This is a fat burning diet pill that boosts the metabolism and curbs appetite. It contains a blend of 3 key ingredients – yerba mate, guarana and damiana. Because Zotrim is a propriety formulation it is not possible to determine ingredient concentrations. However, Zotrim has been evaluated in clinical trials and shown to promote weight loss. Based on clinical trial data the manufacturer states that Zotrim can deliver an average weight loss of 11 lbs in 6 weeks, or 1-2lbs a week. No appreciable side effects have been reported during these clinical studies.

Meratol: While no clinical studies have actually been carried out on Meratol itself – they have been undertaken on individual ingredients. Meratol combines 4 clinically evaluated extracts: brown seaweed extract; capsicum extract; cactus extract; and prickly pear cactus. Meratol simultaneously boosts metabolism, burns calories and inhibits the intake of carbohydrates. Meratol was recently featured in the British Daily Express newspaper where it was praised for aiding weight loss without side effects, or the need to change exercise and eating habits. As there have been no actual clinical studies on Meratol itself, it is difficult to judge how effective this diet pill really is. The manufacturer claims that “if you have more than 14lbs to lose you can expect to lose up to 4lbs in the first week, reducing to 1-2lbs a week thereafter”. This is backed up by numerous positive testimonials posted on the internet. While the side effects of Meratol have not been clinically evaluated user feedback would indicate that there are few if any, if the diet pill is taken at the recommended dose.

Capsiplex: This diet pill is apparently used by high profile celebrities. Capsiplex includes capsicum extract (chili pepper) with a small amount of caffeine, black pepper extract (piperine) and niacin known as the Capsimax Plus formula. Capsicum extract, the key ingredient in Capsiplex, has been shown to boost metabolic rate in clinical trials. However, to experience the full benefits of Capsicum it would be necessary to consume 10 grams on a daily basis. For most people this would cause major irritation to the gastrointestinal tract, particularly the stomach. Using a patented matrix of excipients and coatings the manufacturer of Capsiplex has produced a pill that has no adverse effects on the mouth or stomach. The outer coating has been designed to release the capsicum extract in the intestine, where no discomfort is felt. Capsiplex breaks down in the intestines, so that there is no burning sensation when voiding. The manufacturer claims that an individual with more than 14lbs to lose can expect to lose up to 4lbs in the first week, reducing to 1-2lbs a week thereafter taking the recommended dose of Capsiplex. To date no significant adverse effects have been reported on internet user forums.

Zotrim is a fat burning diet pill that contains a blend of 3 common diet pill ingredients – yerba mate, guarana and damiana. Because Zotrim is a propriety formulation it is not possible to determine ingredient concentrations. However, Zotrim has been evaluated in clinical trials and shown to promote weight loss.

See also: Zotrim Review

Zotrim pros

• Zotrim is manufactured by a reputable company
• Zotrim has been evaluated in numerous clinical trials
• Zotrim has been shown to have no significant short term side effects in clinical studies
• There is a 100% money-back guarantee offered with Zotrim supplements.
• Customer testimonials are posted on the official website

Zotrim cons

• Some ingredients found in Zotrim may not be suitable for some individuals
• A full product ingredient list is not provided for Zotrim on the official website
• Zotrim has to be taken three times daily with water, which may prove to be inconvenient for some users

Zotrim side effects

Although the clinical studies performed on Zotrim revealed no significant side effects, the 3 prominent ingredients contained in this supplement have been reported to cause some adverse reactions in individuals. Without knowing the concentrations of these ingredients, it is difficult to assess whether or not Zotrim could cause health problems for some users.

Due to the fact that Zotrim contains caffeine, people sensitive to caffeine could experience headaches, nausea, jitters or shakes. Zotrim is not intended for children under the age of 16. The potential risks of the 3 major ingredients have not been established clinically for pregnant or nursing women. Zotrim is known to contain at least two different sources of caffeine. Medical practitioners advise nursing or expecting women to limit the amount of caffeine they consume. Additionally, individuals who are allergic to plants, have heart conditions, high blood pressure, smoke, suffer from anxiety, bleeding conditions, have osteoporosis, or have glaucoma should consult a doctor before taking Zotrim. This diet pill does slow stomach empting, so people that has digestive disorders or have a diet with a high fat content should use this diet pill with caution.

It has been documented that the clinical studies performed on Zotrim did not report any significant side effects. However, the ingredients yerba mate, guarana and damiana have been reported to elicit side effects in some individuals at high doses. Unfortunately, the manufacturer does not reveal the concentration of the ingredients in Zotrim.

Zotrim ingredients

A list of Zotrim ingredients is not available on the official website. Only 3 ingredients in the Zotrim formulation have been revealed namely:

Yerba Mate: A South American shrub that contains the xanthine alkaloids caffeine, theobromine and theophylline. Yerba mate contains about half the caffeine of coffee. Theobromine and theophylline are stimulants, although they have a less potent effect on the central nervous system (CNS) than caffeine. Flushing, nausea, vomiting, irritability, nervousness, increased urination and headache may occur with yerba mate. If any of these effects persist or worsen, contact a doctor promptly. Stronger but very infrequent side effects include stomach pain, yellowing eyes and skin, dark urine, fever, muscle twitching and unusually fast/slow/irregular heartbeat.

Guarana: Guarana is a common ingredient in many popular stimulant-based weight loss pills. It is included primarily for its caffeine content (caffeine is a potent thermogenic agent) but it also has anti-oxidant and diuretic properties. Harvested in Brazil and Uraguay, this wild-growing climbing shrub has been used for centuries as a general health-tonic and recently as an energizing drink. Guarana may cause side effects, but many people have no, or minor, side effects. Side effects can include anxiety, diarrhea, headache, increased urination, nausea, nervousness, shakiness, tremors, trouble sleeping, upset stomach and vomiting.

Damiana: A shrub that grows in the South Western United States and Mexico. Damiana herb has been used as a general tonic for both men and women, particularly when hormone-related conditions are present. The herb also has antidepressant, anti-anxiety, diuretic and mild laxative effects. Damiana is relatively safe in regular doses, although the long term effects of Damiana use have not been evaluated. Damiana does have a traditional background as an abortive and therefore should not be taken during pregnancy. Damiana also has a mild hypoglycemic effect, so those on diabetes medication or those who suffer from hypoglycemia must use caution with this supplement. Damiana may interfere with the body’s absorption of iron, and iron levels should be monitored while on this herb. The safety of this supplement in children has not been tested so it should not be used.

Zotrim dosage

The manufacturer recommends that Zotrim is taken 3 times per day with water, at a dose of up to 3 tablets each time depending on body-mass. The best time to take Zotrim is 15 minutes prior to a meal. If breakfast is not normally taken then the manufacturer recommends that just one dose of Zotrim is taken in the morning followed by a further 2 doses with main meals.

Zotrim conclusion

It is disappointing that a full list of ingredients in Zotrim, or their concentrations has not been made available on the official website. This would allow potential users to evaluate all of the ingredients, and better gauge potential side effects.

According to the official website, Meratol simultaneously boosts metabolism, burns calories and inhibits the uptake of carbohydrates. However, no clinical studies appear to have been carried out on Meratol – only on individual ingredients. The manufacturer, Advanced Health Ltd, claims that there are no serious side effects associated with Meratol, but this does not appear to have been verified in a clinical trial of the product itself. Individual ingredients in Meratol could potentially cause side effects in some individuals.

See also: Meratol Review

Meratol side effects

Meratol is not suitable for vegetarians and vegans because the capsules contain gelatine. There is no evidence presented by the manufacturer that clinical studies have been carried out on the safety of Meratol itself. Brown seaweed extract, an ingredient in Meratol has been reported to cause nausea and diarrhea in some individuals, particularly at higher doses. This extract has a high iodine content which could lead to thyroid problems at high doses. On the official Meratol website, the manufacturer states that no iodine related side effects have been seen, but again the manufacturer presents no evidence that Meratol itself has been clinically tested. Some people are allergic to another ingredient in Meratol, prickly pear cactus.

In addition, the effects of potential interaction between the various ingredients in Meratol have not been clinically evaluated.

The manufacturer recommends that the following groups do not take Meratol, or consult a doctor first:

• Pregnant women (consult a doctor first)
• Breastfeeding women
• Cardiovascular patients (consult a doctor first)
• Children (consult a doctor first)

Meratol pros

• The ingredients in Meratol have been individually tested in clinical trials and are believed to be safe for healthy individuals
• There are numerous positive user testimonials
• The manufacturer is well established and has a good reputation in the industry

Meratol cons

• No clinical studies appear to have been carried out on the Meratol diet pill itself, so the weight loss and toxicology claims of the manufacturer have not been scientifically verified
• The official product website has few testimonials
• Meratol does not come with a money back guarantee

Meratol dosage

Meratol is taken once a day (two tablets) in the morning before breakfast. There are 60 capsules in a bottle, which is 1 month’s supply.

Meratol ingredients

Prickly pear cactus: This plant is used in herbal medicine. It is composed of soluble and insoluble dietary fibers. These fibers are claimed to bind dietary fat and thus prevent it from being absorbed in the gastrointestinal tract. Little information is available on the side effects of prickly pear cactus. Dermatitis is the most common adverse reaction to prickly pear. Avoid use during pregnancy and lactation due to the lack of clinical studies. Some individuals are allergic to prickly pear cactus. Symptoms can include chest pains, difficulty breathing, skin rashes, water loss, and an increased frequency of bowel movements. An additional adverse effect may include exacerbation of hypoglycemia if combined with oral hypoglycemic agents.

Brown seaweed extract: Because it is an excellent source of iodine, brown seaweed extract can improve thyroid function, potentially increasing metabolism and energy, and decreasing weight gain. The iodine, calcium and other minerals in brown seaweed extract are readily absorbed by the body, assisting digestion and correcting relevant mineral deficiencies. Brown seaweed extract has been reported to cause nausea and diarrhea in some individuals, particularly at higher doses. This extract has a high iodine content which could lead to thyroid problems at high doses.

Cactus extract: This extract is beneficial in reducing cholesterol levels and promoting weight loss. Cactus extract also has antibacterial and anti-inflammatory effects, and may even ease hangover symptoms. For most healthy adults there are no serious side effects in consuming cactus extract. However, mild side effects in some individuals may include headache, nausea, diarrhea and bloating. Individuals with kidney or liver disorders should not take cactus extract without consulting a doctor first. With diabetic patients extreme caution should be used when taking certain medications to control the disease when consuming cactus extract. Always consult a physician before taking cactus extract due to the risk of developing hypoglycemia (low blood sugar) and other adverse effects.

Capsicum Extract: Red hot chilies or capsicum extract is the principal ingredient in Capsiplex (a weight loss product also made by Advanced Health Ltd which is included in the Meratol formulation) while caffeine, black pepper extract (piperine) and niacin are also present. For a full review of capsicum side effects see: Capsiplex Side Effects. To minimize the side effects of concentrated red hot capsicum extract, the tablet has a specially designed coating. Capsicum has not been evaluated by the FDA for safety, effectiveness or purity. Capsicum contains capsaicinoids, which are the family of compounds that cause the intense heat experienced when consuming chili peppers. Capsanicinoids help to promote thermogenesis, carbohydrate oxidation and stimulate fat oxidation. Side effects for capsicum have been reported infrequently. These include upset stomach, heartburn, hot flushes and diarrhea. However, it is potentially unsafe to take capsicum by mouth in large doses or for long periods of time. In rare cases, this can lead to more serious side effects such as liver or kidney damage.

Meratol conclusion

Meratol is made by a well regarded company, Advanced Health Ltd, in Scotland. They are open about Meratol’s composition, so that it is possible to research the ingredients beyond the information provided on the website. The manufacturer does not back its “no serious side effects” claims with clinical trial data on for Meratol itself, only on individual ingredients (from studies carried out by other companies or research groups). The ingredients in Meratol could potentially cause side effects in some individuals.

“Combo-pilling” is a more radical approach to slimming. It has been used for some time by numerous famous celebrities, and is now becoming increasingly popular with the general public.  Combo pilling involves the dubious practice of combining two or more diet pills, rather than just taking a single pill. Pill combinations include, Xenadrine and Hydroxycut, SlimTron HGS and Hype and Zantrex-3 and Smartburn for Women.The most popular diet pill combination is Zantrex-3 and Relacore. Zantrex-3 is a stimulant-based pill that is claimed to boost fat burning and energy levels, while Relacore is believed to have a calming effect, and to counteract the fat stimulating effects of the stress hormone cortisol. Many claim that the weight loss effects of both pills are considerably enhanced when taken together. Combo-pilling is a potentially dangerous practice because the side effects of diet pills can be amplified when taken together.

How does combo-pilling work?

The basic concept behind combo-pilling is to take two or more diet pills simultaneously to increase metabolism, reduce appetite and enhance mood. The most popular pill cocktail is Zantrex-3 and Relacore. This is claimed by many users to considerably magnify the weight loss benefits that can be achieved by taking the two pills separately. Zantrex-3 is claimed by the manufacturer to promote rapid weight loss through fat burning and to deliver a major energy boost. Relacore is marketed as a mood elevating, anti-stress pill that promises to stop the anxiety hormone cortisol in its tracks, thus reducing belly fat.

To have the optimum weight loss effects it is believed that the diet pill combination should have the following properties:

1. Boost metabolism
2. Enhance thermogenesis
3. Suppress appetite
4. Block carbohydrate absorption
5. Bind dietary fat
6. Cleanse and detoxify
7. Relieve stress

Side-effects of combo-pilling

Taking two or more diet pills in combination can be potentially dangerous because the number of side effects increases and the magnitude of these effects can be amplified. For example, Zantrex-3 side effects include stimulant related effects such as the jitters, increased heart rate, nausea, restlessness and cold sweats. Withdrawal symptoms have also been reported by some users when Zantrex-3 usage is terminated. Side-effects that have been reported by some slimmers taking Relacore include blurred vision, tiredness, and changes in blood pressure.

Combo-pilling pros

• Numerous positive testimonials have been posted claiming enhanced weight loss

Combo-pilling cons

• There is no clinical evidence supporting the use of combo-pilling or information on its safety
• Multiple side effects can be experienced
• Many diet pill brands are of dubious quality and no details of the manufacturer, the country where pills are made, product quality control and purity, or a contact address are provided

Noxycut is blue diet pill for men only. It has a relatively high content of the stimulants Caffeine, Yohimbe and Synephrine. Side effects that have been reported using Noxycut include: Headache, stomach ache, nervousness, anxiety, jitters, irritability, nausea, insomnia, racing heart, chest pains, spots, acne and increased appetite. Unfortunately, there is no clinical data posted on the official website supporting the Noxycut formulation.

See also: Noxycut Review

Noxycut pros

• The effectiveness of Noxycut is supported by some positive testimonials on the internet

Noxycut cons

• Noxycut reviews are mixed with numerous users reporting zero fat loss or muscle gain
• Noxycut has been developed for men only
• Noxycut is a stimulant heavy diet pill
• Noxycut contains relatively high levels of caffeine
• Many users have experienced negative side effects using Noxycut
• Noxycut is not backed by a full guarantee
• Noxycut is illegal in some countries such as Australia, New Zealand and Canada due the inclusion of Yohimbe in the formulation
• There are no contact details for Noxycut other than an email address and a telephone number
• No information is provided on the country where Noxycut is made or the quality control procedures involved in its manufacture

Noxycut dosage

One container of Noxycut contains 75 pills which approximates to a 30-day dosage. The serving size is one capsule.

Noxycut ingredients

Noxycut’s ingredients are:

Tribulus terrestris (80% Saponins; 200 mg): This compound is claimed to elevate testosterone levels, thus increasing muscle mass and enhancing libido. Tribulus is frequently used to promote fat loss. However, to date the clinical trials involving Tribulus have shown no effect on body fat or testosterone production (Int J Sport Nutr Exerc Metab. 2000;10(2):208-215; J Ethnopharmacol. 2005; 101(1-3):319-23). Little is known about the long-term use of Tribulus terrestris consumption in man. As with most herbs, it is best to take breaks from use in order to minimize potential long term tribulus side effects. Side effects reported by Tribulus terrestris users include feeling warmer, slight elevation in heart beat and restlessness. These s side effects are dose dependent and are more common at doses above 500 mg.

Eurycoma longifolia (50 mg): Eurycoma is used as an aphrodisiac. Standardized for 40% glyco saponins and 30% polysacharides, the Eurycoma extract in Noxycut has been shown to help increase IGF1 levels and modulate cortisol levels. Studies on this particular extract have shown that it increases average male serum testosterone level and muscle strength (Phytomedicine. 2003;10(6-7):590-593: Exp Anim. 2000:49(1):35-38; Br. J. Sports Med. 2003;37: 464-470). One of the side effects of high dose Eurycoma root is that it can cause insomnia. Additional reported side effects are increased body temperature, restless and irritability.

L-Glutamine (100 mg): L-Glutamine is used by athletes and bodybuilders to help them recover faster from workouts and competition, and to keep muscles hydrated for maximum growth. However, to obtain optimal results from this compound a higher dose than 100 mg is needed. Even at doses of 3-6 grams there are clinical studies that indicate that glutamine has no beneficial effects on muscle performance (J Strength Cond Res. 2002;16(1):157-160; Sports Med. 2003;33(5):323-345). No side effects have been reported for glutamine. This is not surprising considering the abundance of glutamine in the human body.

Creatine Ethyl Ester (100 mg): Creatine is used as an aid for athletic performance and for muscle development in bodybuilding. Numerous studies have demonstrated Creatines’ effectiveness in enhancing athletic performance (e.g. Med Sci Sports Exerc. 1998;30(1):73-82; Med Sci Sports Exerc. 2002;34(2):332-343). Cramping and bloating are the most common side effects reported by Creatine users. However, with the more easily absorbed creatine ethyl ester variant, these side effects may be eliminated or reduced.

Arginine AKG (100 mg): Arginine Alpha Ketoglutarate (AAKG) has been demonstrated to increase nitric oxide (NO) levels. NO is a molecule in the cardiovascular system that transports oxygen, increases blood flow and delivers nutrients to skeletal muscle. AKG enhances workout performance, which can result in increased muscle mass. In a clinical trial, subjects taking four grams of AAKG three times a day reported no significant side effects, experienced no changes in blood pressure or heart rate, and exhibited no abnormalities on standard tests for general health (Vacanti et al. Sports Nutr Rev J. 2004;1:S10-S11). Some doctors believe that individuals with herpes (either cold sores or genital herpes) should not use arginine supplements, due to the possibility that it might stimulate replication of the virus. No clear interactions between AAKG and other nutrients have been established. At the time of writing, there are no obvious drug interactions with AAKG.

Caffeine (150 mg): This compound is found in many weight loss supplements because it is a recognized fatburner with clinically proven benefits for weight loss (e.g. Am J Clin Nutr. 1989;49(1):44-50; Am J Clin Nutr. 1980;33(5):989-97). Caffeine can cause headaches, diarrhea, anxiety, jitters, insomnia and increased heart rate.

Cinnamon Extract (50 mg): Cinnamon (Cinnamomum verum and Cinnamomum cassia) may have some benefit in lowering blood-sugar levels and may help slow the body’s absorption of fat. Research studies have yielded variable results and it has not yet been clearly established whether taking a cinnamon supplement reduces blood sugar levels with long term use. Chronic extensive surface ulcerations and lip swelling induced by cinnamon have been reported (Cohen and Bhattacharyya. J Am Dent Assoc. 2000;131(7):929-934). Fourteen cases of cinnamon-induced stomatitis have also reported (Miller et al. Oral Surg Oral Med Oral Pathol. 1992;73(6):708-716).

Guggulsterones 2.5% (15 mg): This ingredient is an extract of Commiphora mukul. Another common name for this compound is Guggul. In India Guggul is used to help lower blood cholesterol and triglyceride levels. Studies have shown that Guggal is safe and effective in lowering the various lipid fractions that are known to contribute to coronary heart disease.

Synephrine HCL (15 mg): Synephrine comes from the Citrus aurantium plant. It can help boost fat burning, reduce appetite and increase energy. However, clinical studies have shown that Citrus aurantium promotes a relatively small increase in thermogenesis. Side effects of Synephrine include headache, blurred vision, nervousness, anxiety, insomnia, tremor, dry mouth, increased heart rate and blood pressure. Synephrine may also make urination more difficult. Individuals with a history of high blood pressure, anxiety, urinary problems or cardiac disease are advised to consult a physician before taking Synephrine. In addition, combining Synephrine with other medicines with similar side effects could lead to dangerous complications.

Yohimbe (1.5 mg): This ingredient is a tree bark with a variety of pharmacologically active chemicals. A number of studies support Yohimbe’s positive effect on weight loss (e.g. Isr J Med SCI 1991. 27(10):550-6), but its effects are not dramatic. Serious side effects associated with products containing Yohimbe have been reported to the FDA, including renal failure, seizures and death. The major alkaloid in Yohimbe is Yohimbine, a chemical that induces vasodilation, thus lowering blood pressure. Additional side effects can include anxiety attacks. At high doses, Yohimbine acts as a monoamine oxidase (MAO) inhibitor. MAO inhibitors can cause serious adverse effects when taken in combination with tyramine-containing foods (e.g. liver, cheese and red wine) or with over-the-counter (OTC) products containing phenylpropanolamine, such as nasal decongestants and diet products. Individuals taking Yohimbe are warned to avoid these foods and OTC products due to the increased risk of adverse effects. Yohimbe should also be avoided bypeople suffering from hypotension (low blood pressure), diabetes, and heart, liver or kidney disease. Symptoms of overdose include weakness and nervous stimulation followed by paralysis, fatigue, stomach disorders and ultimately death.

Noxycut conclusion

Noxycut is not an ordinary diet pill and is not recommended for the average dieter seeking to lose weight. Although Noxycut does not contain ephedra it is a stimulant heavy diet pill. Yohimbe in Noxycut comes with some serious side effects, for example, raised heart rate. Consumers should be cautious of the claims made for Noxycut and be careful to consider the potential health consequences of taking this diet pill.

Lipozolve is a diet pill containing an antioxidant (Resveratrol), two appetite suppressants (Hoodia and Chá de Bugre) and a fat burner (Green Tea). Lipozolve side effects include headaches, irritability, jitteriness, nervousness, insomnia and elevated heart rate.

See also: Liposolve Review

Lipozolve pros

• The official website offers a money-back guarantee

Lipozolve cons

• Lipozolve is a propriety blend. Are there high enough doses of the active ingredients for optimal weight loss effectiveness?
• There are few testimonials on the official website
• Lipozolve contains caffeine
• Some users have reported side effects after taking Lipozolve
• No details of the manufacturer, the country where Lipozolve is made, product quality control and purity, or a contact address are given on the website – always a cause for concern

Lipozolve ingredients

Resveratrol: This compound is an antioxidant found in red wine, red grapes, raspberries, mulberries, blueberries, cranberries, peanuts, certain pine trees and knotweed. Resveratrol is popular with women because they believe that it promotes weight loss. A study has found that mice fed a high-fat diet that included resveratrol had a similar average weight to mice eating a low-fat diet without resveratrol. This compound has mild estrogenic activity that has not yet been evaluated in man. Until more is known it is recommended that woman with estrogen-sensitive conditions, including some cancers, consult a doctor before taking resveratrol supplements to avoid potential side effects. It is also recommended that to avoid possible growth inhibition side effects resveratrol supplementation be avoided by children and women who are pregnant, nursing, or trying to conceive. In addition, because resveratrol acts as a blood thinner it is suggested that people already on blood thinning medications avoid resveratrol. The same goes for other prescription drugs – always consult a doctor first. Reversible side effects have been reported in subjects taking high dose (0.5 – 1.0 gram) of resveratrol. They included diarrhea, abnormal blood tests, thinning of the blood, headaches and anxiety. Resveratrol’s long-term safety has yet to be evaluated.

Green tea: Green tea has been demonstrated in clinical studies to promote modest weight loss. However, it needs to be taken in relatively high doses, and to contain high levels of catechins. In Lipozolve, the amount of green tea present in the formulation is not indicated. Because green tea contains caffeine individuals sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Chá de Bugre: This is a tree commonly found in Brazil. It produces a red fruit similar to a coffee bean which can be roasted and made in to a coffee substitute. Chá de Bugre is claimed to act as an appetite suppressant. Chá de Bugre is also believed to stimulate the metabolism and thus promote fat burning, although no clinical studies have been carried out. Cha de Bugre contains caffeine, potassium, allantoin and allantoic acid. Some users of Chá de Bugre have complained of dry mouth, restlessness, anxiety, insomnia and headache, presumably due to its caffeine content.

Hoodia gordonii: Hoodia gordonii is a cactus from the aloe family that grows in the Kalahari Desert. In South Africa, Hoodia is now on the list of endangered plant species, and is not actually supposed to be exported. The vast majority of Hoodia products on the market contain very little, if any, active Hoodia. There is a lack of published studies on the safety of Hoodia in man. A former researcher working for Pfizer (the pharmaceutical company that licensed the rights to develop Hoodia but later dropped them), stated in a letter to The New York Times that there were indications of adverse effects on the liver caused by components other than the active ingredient p57. These components could not easily be removed during processing. Assuming that Hoodia can affect liver function, it may also interact with some drugs. Individuals with diabetes should be wary of Hoodia. Hoodia is believed to trick the brain into thinking that there is enough blood sugar in the blood, when levels are actually low – triggering suppression of appetite. Without proper feedback to the brain it is possible that blood sugar could drop dangerously low while taking Hoodia. Hoodia is also believed to suppress thirst. There have been unconfirmed reports of shepherds in Africa who took Hoodia and died of dehydration because they did not feel thirsty. As a general precaution Hoodia should be avoided by pregnant or nursing women, children, or people with liver or kidney disease because its safety has not been established in these groups.

Lipozolve dosage

Each bottle of Lipozolve contains 60 capsules or one month’s supply.

Manufacturers’ contact details

Website: http://www.lipozolve.com/

An internet search revealed that Lipozolve is owned by JP Innovative Marketing Inc., 1341 SW 56th Ave, Plantation, FL 33317.