MyoRipped is a fat burning, muscle building, libido and energy boosting pill for men. MyoRipped contains the stimulant caffeine. Side effects that have been reported by some MyoRipped users include stomach ache, headache, anxiety, jitters, nervousness, nausea and insomnia. Creatine in MyoRipped can also cause bloating and indigestion.

See also: MyoRipped Review

MyoRipped pros

• MyoRipped is reported to give the libido a lift
• The effectiveness of MyoRipped is supported by positive reviews and testimonials on the internet
• MyoRipped comes with a money-back guarantee

MyoRipped cons

• MyoRipped reviews are mixed with some users reporting no positive results with regard to weight loss and muscle gain
• MyoRipped is designed exclusively for men
• MyoRipped contains caffeine and other stimulants
• Some users report experiencing side effects using MyoRipped
• There are no contact details for MyoRipped other than an email address and telephone number
• No details are provided on where MyoRipped is manufactured or the quality control procedures involved

MyoRipped side effects

MyoRipped contains the stimulant caffeine. Side effects that have been reported by some MyoRipped users include stomach ache, headache, anxiety, jitters, nervousness, nausea and insomnia. Creatine in MyoRipped can also cause bloating and indigestion. Individuals with prostate health issues may want to consult with their doctor before taking MyoRipped. Women are strongly advised not to take MyoRipped as the testosterone stimulating ingredients may disrupt female hormone levels.

MyoRipped ingredients

MyoRipped’s ingredients are: Caffeine, 1,3 Dimethylamylamine, Beta Alanine, Creatine Ethyl Ester, Tribulus Terrestris, Eurycoma Longfolia, Horny Goat Weed, Cissus Quadrangularis, Coleus Forskohlii, 20-Hydroxyecdysterone, Vitamin B6, Vitamin B12, Chromium Picolinate.

Looking at the ingredients in greater detail:

Beta Alanine: Beta-alanine is a naturally occurring, nonessential amino acid. Beta-alanine improves muscular strength and endurance by increasing the amount of carnosine in the body. Beta-alanine is considered to be safe for healthy adults. However, overconsumption of this supplement may cause skin flushing or irritation.

Caffeine: This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, jitters, headaches, diarrhea, insomnia and increased heart rate.

Chromium polynicotinate: This ingredient is a niacin-bound chromium complex that plays a key role in the regulation of insulin function, and the maintenance of healthy blood sugar and cholesterol levels. Chromium is involved in carbohydrate, protein and fat metabolism. The clinical studies that have been carried out on chromium have been inconclusive; some demonstrating that it had a subtle effect on weight loss and others showing that it was ineffective. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change, and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Cissus quadrangularis: This is an herbal supplement used in Ayurvedic and alternative medicine. Safety studies in rats showed no toxic effects at dosages as high as 2000 mg/kg of body weight. Commercial products containing Cissus quadrangularis seem to be safe when used appropriately in adults, short-term for up to 6-8 weeks. Some people who took Cissus quadrangularis experienced side effects such as headache, flatulence, dry mouth, diarrhea, and insomnia. But there is not enough information to know how often these side effects might occur.

Coleus forskholii: This herb is common to many fat burners. While the positive effects of Coleus forskohlii on weight loss have been established in one study (Journal of Obesity Research 2005 – Body composition and hormonal adaptations associated with Forskolin consumption in overweight and obese men), the results were not particularly strong. It has been demonstrated to enhance lipolysis and may also inhibit fat storage. A clinical study published in the Journal of the International Society of Sports Nutrition (2005: 2(2): 54-62) indicated that there were no significant side effects – despite previous research indicating that Coleaus forskohlii may cause an increase in heart rate and decrease in blood pressure.

Creatine Ethyl Ester: Creatine is used as an aid for athletic performance and for muscle development in bodybuilding. Numerous studies have demonstrated Creatines’ effectiveness in enhancing athletic performance (e.g. Med Sci Sports Exerc. 1998;30(1):73-82; Med Sci Sports Exerc. 2002;34(2):332-343).Cramping and bloating are the most common side effects reported by Creatine users. However, with the more easily absorbed creatine ethyl ester variant, these side effects may be eliminated or reduced.

1,3 Dimethylamylamine: This ingredient is also known as Geranium extract and DMAA. It functions as a central nervous system (CNS) stimulant. Although there are currently no clinical studies to support the weight loss enhancing claims being made by the manufacturer, it is quite possible that as a CNS stimulant, it does promote fat burning . Geranium extract is a very potent stimulant, and depending on the concentration present (unfortunately not revealed) may provide a very powerful energy boost, especially when combined with caffeine, as it is in the OxyElite Pro formulation. Individuals sensitive to stimulants or with underlying medical conditions such as high blood pressure, cardiovascular disease, etc should consult a medical practitioner before considering taking geranium.

Eurycoma Longifolia: Eurycoma is used as an aphrodisiac. Studies have shown that it increases average male serum testosterone level and muscle strength (Phytomedicine. 2003;10(6-7):590-593: Exp Anim. 2000:49(1):35-38; Br. J. Sports Med. 2003;37: 464-470). One of the side effects of high dose Eurycoma root is that it can cause insomnia. Additional reported side effects are increased body temperature, restless and irritability.

Horny Goat Weed: Apart from being an established natural aphrodisiacs and performance enhancer, Horny Goat Weed is also a good heart and circulation tonic. Possible minor side effects may include dizziness, thirst, vomiting and dry mouth. Theoretically, horny goat weed could increase the risk of bleeding, including dangerous internal bleeding. This risk is probably most significant for individuals with bleeding disorders or who take blood thinning medications. Other possible serious side effects of horny goat weed include a rapid heart rate (tachycardia) and signs of an allergic reaction.

20-Hydroxyecdysterone: This is a natural anabolic agent. From anecdotal reports, 100mg of ecdysterone can dramatically increase nitrogen retention in muscle. This nitrogen-sparing effect can benefit the bodybuilder by increasing the amount of muscle that can be built up. Ecdysterone is believed to be safe, and has no known side effects.

Tribulus Terrestris: This compound is claimed to elevate testosterone levels, thus increasing muscle mass and enhancing libido. Tribulus is frequently used to promote fat loss. However, to date the clinical trials involving Tribulus have shown no effect on body fat or testosterone production (Int J Sport Nutr Exerc Metab. 2000;10(2):208-215; J Ethnopharmacol. 2005; 101(1-3):319-23). Little is known about the long-term use of Tribulus terrestris consumption in man. As with most herbs, it is best to take breaks from use in order to minimize potential long term tribulus side effects. Side effects reported by Tribulus terrestris users include feeling warmer, slight elevation in heart beat and restlessness. These s side effects are dose dependent and are more common at doses above 500 mg.

Vitamin B6: Vitamin B6 plays a key role in the metabolism of fats, particularly fatty acids which are unsaturated. This vitamin also helps with the regulation and production of the thyroid hormone, thyroxin. Adverse effects have only been documented from vitamin B6 supplements and never from food sources. Although vitamin B6 is a water-soluble vitamin and is excreted in the urine, doses of pyridoxine in excess of the RDI over long periods of time thus result in painful and ultimately irreversible neurological problems. The primary symptoms are pain and numbness of the extremities, and in severe cases difficulty walking. The tolerable upper limit has been set by the US FDA at 100 mg/day in 2000.

Vitamin B12: This vitamin plays an important role in the normal functioning of the brain and nervous system. Vitamin B12 is believed to be safe when used orally in amounts that do not exceed the recommended dietary allowance (RDA). The RDA for vitamin B12 in pregnant women is 2.6 µg per day and 2.8 µg during lactation periods. There is insufficient reliable information available about the safety of consuming greater amounts of vitamin B12 during pregnancy. Vitamin B12 supplements in theory should be avoided in people sensitive or allergic to cobalamin, cobalt, or any other product ingredients. However, direct allergy to a vitamin or nutrient is extremely rare.

MyoRipped conclusion

MyoRipped is not a regular diet pill and is not recommended for the average person looking to lose weight. Several of the ingredients in MyoRipped are stimulants that can cause side effects in some users. These may include headaches, jitteriness, and insomnia.

ZCA Stack was developed from the original ECA Stack formula which contained the now banned ephedra. It is a stimulant heavy pill containing Advantra Z, caffeine and white willow bark extract. Some users have reported side effects including headaches, jitteriness, nervousness, irritability, insomnia, high blood pressure and an elevated heartbeat.

See also: ZCA Stack Review

ZCA Stack pros

• ZCA Stack comes with a 30-day money back guarantee

ZCA Stack cons

• ZCA Stack has received mixed reviews on independent consumer sites
• ZCA Stack is a stimulant heavy diet pill and can cause side effects
• Some of the claims made on the ZCA Stack website appear exaggerated
• No details of the manufacturer, the country where ZCA Stack is made, product quality control and purity or a contact address are given on the website – always a red flag

ZCA Stack side effects

Reported ZCA Stack side effects include headaches, jitteriness, nervousness, irritability, insomnia, high blood pressure and an elevated heartbeat. The manufacturer recommends that ZCA Stack should not be taken if pregnant or breast feeding. ZCA Stack should not be used by anyone under the age of 18. Individuals with a history of heart problems or high blood pressure should consult a physician before using ZCA Stack. Certain supplements or medications may interact with ZCA Stack. Inform a doctor or pharmacist of all prescription and over-the-counter products before taking ZCA Stack.

ZCA Stack dosage

ZCA Stack is sold as micro-gel capsules and it is recommended to be taken at a dose of 2 capsules per day, one before breakfast and the other before the afternoon meal. The manufacturer suggests starting by taking just one capsule per day to assess tolerance levels, due to the high stimulant content. There are 60 servings (120 capsules) per container.

ZCA Stack ingredients

One capsule of ZCA Stack contains Advantra Z (standardized for 25mg synephrine), 250mg caffeine and 250mg white willow bark. Other ingredients: Magnesium stearate.

Looking at the ingredients in greater detail:

Advantra-Z: Advantra-Z is a patented form of Synephrine, an alkaloid that is derived from Citrus aurantium. It is considered as a safe alternative to the now banned ephedra and is believed to promote thermogenesis. Manufacturers claim that Synephrine provides the “fat burning” effects of Ephedra, but without side effects such as sleeplessness, jitters, elevated blood pressure, etc. There are studies, however, that indicate that Synephrine can elevate blood pressure and heart rate (e.g. Ann. Pharmacother. [2006] 40(1):53-7).

Caffeine: This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, headaches, diarrhea, insomnia and increased heart rate. ZCA Stack does contain other stimulants such as Advantra-Z that can cause jitters and other caffeine-type side effects.

White willow bark: White willow was used in ECA (ephedra/caffeine/aspirin) fat burners, although there is limited evidence that it enhanced this stack in any way. In non-ephedra fat burners such as ZCA Stack, it is unlikely to have any value, except as an anti-inflammatory, a fever reducer, an analgesic, an anti-rheumatic and an astringent. There are some possible side effects due to the active ingredient salicin. This is known to cause ulcers, and overdoses will lead to side effects such as skin rash, nausea, vomiting, tinnitus and kidney inflammation. Individuals with a known allergy to aspirin or have blood clotting issues should avoid white willow bark.

Total Lean Burn 60 is manufactured by GNC, a company which owns an international network of nutritional supplement stores. It is a stimulant heavy diet pill. Side effects that have been reported for Total Lean Burn 60 include lightheadedness, jitters, shakes, anxiety, irritability, headache, rapid heartbeat, stomach upset and cramping, and nausea. It is advisable to consult a doctor prior to taking Total Lean Burn 60 if pregnant, nursing or taking medication, or if you have a medical condition. Due to the relatively high content of grape skin and seed extract use of Total Lean Burn 60 should be discontinued two weeks prior to surgery.

See also: GNC Total Lean Burn 60 Review

Total Lean Burn 60 pros

• Total Lean Burn 60 is manufactured to a high standard by a well established company
• Total Lean Burn 60 has been evaluated clinically, albeit in a limited study
• Total Lean Burn 60 can be purchased both in stores and online

Total Lean Burn 60 cons

• There are numerous negative testimonials
• Some users claim that Total Lean Burn 60 tastes bad
• Total Lean Burn 60 is a stimulant heavy diet pill and side effects have been reported
• Sugar, in the form of dextrose, has been added to Total Lean Burn 60

Total Lean Burn 60 dosage

The manufacturer recommends taking two tablets daily with water before breakfast. Do not take prior to bedtime. Each bottle contains 60 tablets.

Total Lean Burn 60 ingredients

Two tablets of Total Lean Burn 60 contain the following ingredients:

• Guarana Seed Extract (36% caffeine = 180mg) (495 mg)
• Black Tea Leaves Extract (272 mg)
• MegaNatural Grape Skin and Seed Extract (210 mg)
• Ginger Root Extract (200 mg)
• MegaNatural Gold Grape Seed Extract (125 mg)
• Dill Weed Extract (5 mg)

Other Ingredients: Dextrose, Natural Vanilla Flavor, Cinnamon bark extract, FD&C Yellow 6 Lake, FD&C Red #40 Lake, Titanium Dioxide (Natural Mineral Whitener), Cellulose.

Looking at the ingredients in greater detail:

Guarana Seed Extract: Guarana is a common ingredient in many popular stimulant-based weight loss pills. It is included primarily for its caffeine content (caffeine is a thermogenic agent) but it also has anti-oxidant and diuretic properties. Guarana may cause side effects that can include: anxiety, diarrhea, headache, increased urination, nausea, nervousness, shakiness, tremors, trouble sleeping, upset stomach and vomiting.

Black Tea Leaves Extract: Black tea extract contains caffeine. Too much caffeine can cause an array of side effects including restlessness, irritability, anxiety, heartburn, headaches, high blood pressure, sleeplessness, rapid heartbeat and nausea.

Grape Seed Extract: This extract contains a number of flavonoids and other compounds with significant antioxidant properties. It has been found to be a strong neutralizer of free radicals. A small clinical study has suggested that grape seed extract could be a useful for weight management (European Journal of Clinical Nutrition. 2004;58:667-673). Grape seed extract side effects may include headaches, itchy dry scalp, dizziness, nausea, abdominal pain, sore throat and cough. In theory, grape seed extract could increase the risk of bleeding. This risk is will be most significant for individuals with a bleeding disorder or who take blood thinning medications. A doctor should be consulted if any signs of bleeding are developed, such as easy bruising, cuts or scrapes that are slow to stop bleeding or signs of gastrointestinal bleeding, vision or speech changes, weakness or numbness in an arm or leg, or severe headache. Immediate medical attention should be sought if any signs of an allergic reaction to grape seed extract appear, such as a rash, hives, itching, swelling of the mouth, lips, tongue, or throat, or wheezing or other difficulty breathing.

Ginger Root Extract: Ginger (Zingiber officinale) contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Side effects associated with ginger are rare, but if taken in excessive doses the herb may cause mild heartburn, diarrhea and irritation of the mouth.

Dill Weed Extract: Dill (Anethum graveolens) is believed to alleviate the symptoms of colds and flu, and has been used to treat various digestive and intestinal problems. Reports relating to the side effects of dill are limited, the most common being dermatitis. Dill weed is contraindicated in patients who require a low-salt diet because of its high sodium content. Dill should be used cautiously by people with plant allergies because it has allergenic components that may demonstrate cross-sensitivity in some individuals.

This article is for educational purposes only. Practicalweightloss does not provide medical advice, diagnosis or treatment.

Hi Tech Pharmaceuticals Lipodrene SR contains stimulants and can have side effects that include headache, nausea, nervousness, jitters, racing heart and dizziness.

See also: Hi Tech Pharmaceuticals Lipodrene SR Fat Burner Review

Lipodrene SR pros

• There are positive testimonials with regard to weight loss using Lipodrene SR

Lipodrene SR cons

• Lipodrene SR is a propriety blend. Are there high enough doses of the active ingredients to get the job done?
• The official product website has no testimonials
• Lipodrene SR is not supported with a money back guarantee
• Lipodrene SR contains stimulants and side effects have been reported

Lipodrene SR dosage

There are 90 Lipodrene SR tablets in each container. The manufacturer recommends taking 3 tablets daily.

Lipodrene SR ingredients

The Lipodrene SR ingredients are as follows:

Citrus aurantium (standardized for synephrine): Citrus aurantium is a fruit known as Zhi Shi in traditional Chinese medicine and as bitter orange in other countries. It contains synephrine, a compound that is structurally related to Ephedrine, as well as Octopamine and Tyramine. Synephrine has been claimed to increase metabolic rate and fat breakdown, but this is not supported by clinical data which indicated no significant effect on weight loss (Am J Cardiol. 2004;94:1359-1361). It also acts as a mild appetite suppressant and an energy booster. Reported side effects of synephrine include dry mouth, headache, nervousness, anxiety, insomnia, tremor, blurred vision, increased heart rate and blood pressure. Synephrine may also reduce the ability to urinate. It is advisable to consult a doctor if you have any history of high blood pressure, anxiety, urinary problems or cardiac disease. In addition, combining decongestants such as synephrine with other medicines with similar side effects may lead to dangerous complications.

Coleus forskohlii: This herb is common to many fat burners. While the positive effects of Coleus forskohlii on weight loss have been established in one study (Journal of Obesity Research 2005 – Body composition and hormonal adaptations associated with Forskolin consumption in overweight and obese men), the results were not particularly strong. It has been demonstrated to enhance lipolysis and may also inhibit fat storage. A clinical study published in the Journal of the International Society of Sports Nutrition (2005: 2(2): 54-62) indicated that there were no significant side effects – despite previous research indicating that Coleaus forskohlii may cause an increase in heart rate and decrease in blood pressure.

Commiphora mukul: This ingredient is the standardized extract of a resin of a tree native to India. Another common name for this compound is Guggul. In India Guggul is used to help lower blood cholesterol and triglyceride levels. Studies have concluded that Guggal is safe and effective in lowering the various lipid fractions that are known to contribute to coronary heart disease.

Coryphantha macromeris extract: This is a cactus, and although there do not appear to be any clinical studies supporting its effectiveness as a fat burner, it is a known stimulant. Coryphantha macromeris is reportedly used as a traditional hallucinogen by native American shamans. Some users have reported side effects such as waves of intense nausea and distorted vision.

Green tea: Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins. In Lipodrene SR, the amount of green tea present in the formulation is not indicated. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Hoodia gordonii: Hoodia gordonii is a cactus from the aloe family that grows in the Kalahari Desert. In South Africa, Hoodia is now on the list of endangered plant species, and is not actually supposed to be exported. The vast majority of Hoodia products on the market contain very little, if any, active Hoodia. There is a lack of published studies on the safety of Hoodia in man. A former researcher working for Pfizer (the pharmaceutical company that licensed the rights to develop Hoodia but later dropped them), stated in a letter to The New York Times that there were indications of adverse effects on the liver caused by components other than the active ingredient p57. These components could not easily be removed during processing. Assuming that Hoodia can affect liver function, it may also interact with some drugs. Individuals with diabetes should be wary of Hoodia. Hoodia is believed to trick the brain into thinking that there is enough blood sugar in the blood, when levels are actually low – triggering suppression of appetite. Without proper feedback to the brain it is possible that blood sugar could drop dangerously low while taking Hoodia. Hoodia is believed to suppress thirst. There have been unconfirmed reports of shepherds in Africa who took Hoodia and died of dehydration because they did not feel thirsty. As a general precaution Hoodia should be avoided by pregnant or nursing women, children, or people with liver or kidney disease because its safety has not been established in these groups.

Naringin: A bioflavanoid found in grapefruit, giving it its bitter flavor. Naringin works synergistically with other nutrients, increasing their bio-availability and extending their effects in the body. It also interferes with enzyme activity in the intestines, and therefore can inhibit the breakdown of certain drugs. Naringin has been shown to be non-toxic at levels many times greater than the recommended dosages. Even when taken daily, naringin seldom produces a significant allergic reaction. However, people who are allergic to citrus fruits should exercise caution in the use of naringin.

Phenylethylamine (PEA): An alkaloid that functions as a neurotransmitter in the brain, and is believed to boost levels of dopamine. The increase in dopamine promotes a feeling of wellbeing. It is claimed to have appetite suppressing effects as well. Side effects of phenylalanine that are common but not serious include heartburn, nausea, constipation and mild headaches. Serious side effects associated with phenylalanine include insomnia, confusion, dizziness or intense headache. An individual experiencing these symptoms should consult with a physician before continuing phenylalanine doses. Severe side effects associated with phenylalanine include tightness or sharp pain in the chest, difficulty breathing and a sudden increase in heart rate or blood pressure. Symptoms of allergic reaction to phenylalanine include sudden rash or hives and swelling of the face, neck, lips or tongue. An individual experiencing these side effects should seek immediate emergency medical attention. Phenylalanine has the potential to adversely interact with antipsychotic medications prescribed to treat schizophrenia, depression and bipolar disorder such as thioridazine, clozapine and haloperidol. This may result in symptoms of tardive dyskinesia (involuntary movements of the limbs, facial muscles and tongue). Phenylalanine may also diminish the effectiveness of levodopa, a medication prescribed to ease the symptoms of Parkinson’s disease.

Yohimbe: This is a tree bark containing a variety of pharmacologically active chemicals. A number of studies support Yohimbe’s positive effect on weight loss (e.g. Isr J Med SCI 1991. 27(10):550-6). However, its effects are not dramatic. Serious side effects associated with products containing Yohimbe have been reported to the FDA, including renal failure, seizures and death. The major alkaloid in Yohimbe is Yohimbine, a chemical that induces vasodilation, thereby lowering blood pressure. Yohimbine is also used as a prescription drug in the United States. Additional side effects may include central nervous system stimulation that causes anxiety attacks. At high doses, Yohimbine acts as a monoamine oxidase (MAO) inhibitor. MAO inhibitors can cause serious adverse effects when taken in combination with tyramine-containing foods (e.g. liver, cheese and red wine) or with over-the-counter (OTC) products containing phenylpropanolamine, such as nasal decongestants and diet products. Individuals taking Yohimbe are warned to avoid these foods and OTC products because of the increased likelihood of adverse effects. Yohimbe should also be avoided by individuals suffering from hypotension (low blood pressure), diabetes, and heart, liver or kidney disease. Symptoms of overdose include weakness and nervous stimulation followed by paralysis, fatigue, stomach disorders and ultimately death.

5-hydroxytryptophan: 5-HTP is often used to treat mild depression due to it being a precursor to serotonin (a chemical neurotransmitter found in the brain). There is some evidence 5-HTP may promote weight loss (Am J Clin Nutr. 1992;56:863-867; J Neural Transm. 1989;76:109-117), but only when taken in large doses (one study used 900 mg per day). 5-HTP side effects from high doses (70 to 100 mg or more) include nausea and vomiting, stomach cramps, nightmares and decreased sex drive. Tiredness and sleepiness can occur after several days or weeks of use. Long term side effects are not fully known. There may be some people who have a biochemical abnormality in metabolizing 5-HTP. Regular long term use is not recommended at this time.

OxyELITE Pro is a stimulant heavy fat burning diet pill that can have side effects. These side effects can include queasiness, dizziness, nausea, racing heart, hypertension, headache, restlessness, nervousness, insomnia or irritability. There appear to be some gender specific side effects. Some men have reported erection issues and women have been known to have hot flashes. As indicated by the manufacturer, it is not advisable to exceed the recommended dose of OxyElite Pro. DMAA is a powerful stimulant. Individuals new to stimulant-based fat burners, sensitive to caffeine and other stimulants, or with health problems should consider avoiding this product. This diet pill should not be taken for longer than eight weeks in a single cycle, and should not be mixed with prescription medications.

See also: OxyELITE Pro Review

OxyElite Pro advantages

• OxyElite Pro is manufactured to a high standard in the US
• Warnings related to the use of OxyElite Pro are listed
• There are numerous positive testimonials as to the effectiveness of OxyElite Pro

OxyElite Pro disadvantages

• OxyElite Pro is a stimulant heavy diet pill and can cause side effects
• OxyElite Pro side effects can include queasiness, dizziness, nausea, restlessness, nervousness, insomnia or irritability
• Individuals taking prescription medications are advised not to take OxyElite Pro
• OxyElite Pro is a propriety blend. Are there high enough doses of the active ingredients for optimal effectiveness?
• The official OxyElite Pro has no testimonials
• There is no 100 percent satisfaction guarantee offered with OxyElite Pro

OxyElite Pro ingredients

A single dose/capsule contains 219.5 mg of ingredients. The ingredients are a proprietary blend of the following: Bauhinia purpurea L., Bacopa monniera, 1,3-Dimethylamylamine, Cirsium oligophyllum and Rauwolscine (Rauvolfia canescens L.). Other Ingredients are modified starch, gelatin, vegetable stearate, silicon dioxide, Red 3, Blue 1, Red 40 and titanium dioxide color.

Looking at the ingredients in greater detail:

Caffeine: This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, jitters, headaches, diarrhea, insomnia and increased heart rate.

Bauhinia purpurea: A shrub that is commonly grown in Asia and employed extensively in Ayurvedic medicine. Animal studies suggest that Bauhinia helps maintain thyroid hormone levels. However, no similar clinical studies involving Bauhinia have been carried out.

Bacopa monniera: This herb is used to enhance focus and concentration. It is included in the OxyElite Pro formulation for its supposed thyroid regulating effects (J Ethnopharmacol. 2002;81(2):281-285). One study reported cases of dry mouth, nausea and muscle fatigue in volunteers who ingested Bacopa (Psychopharmacology. 2001;156:481-484).

1,3-Dimethylpentylamine Hydrochloride: This ingredient is also known as Geranium extract, 1-3 Dimethylamlyamine and DMAA. It functions as a central nervous system (CNS) stimulant. Although there are currently no clinical studies to support the weight loss enhancing claims being made by the manufacturer, it is quite possible that as a CNS stimulant, it does promote fat burning. Geranium extract is a very potent stimulant, and depending on the concentration present (unfortunately not revealed) may provide a very powerful energy boost, especially when combined with caffeine, as it is in the OxyElite Pro formulation. Individuals sensitive to stimulants or with underlying medical conditions such as high blood pressure, cardiovascular disease, etc should consult a medical practitioner before considering taking geranium.

Cirsium oligophyllum: Use of this plant in the OxyElite Pro formulation is based on an animal study (Int J Biol Sci 2009;5(4):311-318) which suggested that the extract could reduce bodyweight and fat mass, and appeared to specifically target subcutaneous fat mass rather than visceral fat mass. However, there is no clinical data to indicate that a similar effect occurs in man.

Rauwolscine: This ingredient is also known as alpha-yohimbine or corynanthidine, a yohimbine alkaloid that can act as an alpha 2-adrenoceptor antagonist. Alpha-yohimbine is a steroisomer of yohimbine. It may cause less side effects than yohimbine — less tachycardia, blood pressure elevation and anxiety.

OxyELITE Pro dosage

A single capsule of OxyElite Pro represents a single serving, and there are 90 capsules in each container.

The manufacturer recommends beginning by taking 1 capsule on an empty stomach before breakfast for the first 3 days. An additional 1 capsule six to eight hours later on an empty stomach may be taken starting on day 4. Once the above steps have been carried out, an additional capsule may be added to the morning dose. The majority of users will not need to increase this dose. To quote the manufacturer “Under no circumstances should the initial dose be exceeded or the warnings on this bottle be ignored. DO NOT USE OxyELITE Pro FOR LONGER THAN 8 WEEKS FOLLOWED BY A SUBSEQUENT 4 WEEK BREAK. DO NOT EXCEED 3 CAPSULES IN ANY 24 HOUR PERIOD. Exceeding the recommended amounts or not following directions may lead to unwanted side effects. Consume at least 125 Fl. Oz. of liquid per day for men and 91 Fl. Oz. of liquid per day for women while taking this product. Warning: This product is only intended to be consumed by healthy adults 18 years of age or older. Pregnant or nursing women should not use this product. Consult with your health care provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAO-B inhibitor or any other medication, including but not limited to MAOIs, SSRIs or any other compounds with serotonergic activity This product contains caffeine and should not be taken by individuals wishing to eliminate this ingredient from their diet. Discontinue use 2 weeks prior to surgery. Do not use in combination with caffeine or any stimulants from other sources whatsoever, including but not limited to, coffee, tea, soda and other dietary supplements or medications. Do not combine with alcohol. Discontinue use and immediately consult your health care professional if you experience any adverse reaction to this product. Do not exceed recommended serving”.

Accuslim Advanced Chromium Complex is a stimulant heavy diet pill. The Accuslim formulation contains numerous ingredients that are used routinely in fat burners. Stimulants in the formulation can cause side effects in some users.

See also: Accuslim Review

Accuslim pros

• Offers a 100% money back guarantee, less shipping & handling
• The manufacturer promotes a low fat diet and exercise

Accuslim cons

• Accuslim contains stimulants that can cause side effects
• Accuslim is a stimulant heavy diet pill
• Few testimonials on the official Accuslim website and no before and after photos
• The Accuslim manufacturer, the country of manufacture or the quality control procedures are not disclosed on the official website
• Some of the Accuslim ingredients are not documented to aid in weight loss

Accuslim side effects

The ingredients include stimulants such as caffeine. These relatively high amounts of stimulants can cause side effects in some users. The most common side effects of Accuslim are:

• irritability
• restlessness
• nervousness
• upset stomach or cramps
• dizziness
• nausea
• heart palpitations

Accuslim is not recommended for individuals with a history of heart, kidney, liver or thyroid disease.

Accuslim ingredients

Accuslims’ ingredients are:

• Chromium 300 mcg
• Vanadium 100 mcg
• Advantra Z 600 mg
• Rhodiola Rosea 300 mg
• Garcinia Cambogia 1,500 mg
• Green Tea Leaf 400 mg
• Ginseng 300 mg
• Eleuthero 250 mg

Looking at the ingredients in greater detail:

Chromium: Chromium plays an important role in insulin production, which is key to the regulation of blood sugar levels. Chromium is also involved in carbohydrate, protein and fat metabolism. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Vanadium: This element functions as an insulin mimic and has been shown to inhibit the synthesis of cholesterol. Although the use of high doses of vanadium supplements remains controversial, there are studies that suggest positive benefits in using vanadium to treat certain health conditions. For example, insulin sensitivity has been shown to improve in animals and human subjects treated with vanadium, suggesting that vanadium may be useful in helping to lower blood sugar levels in diabetics (e.g. Mol Cell Biochem. 2001; 218(1-2):93-96; Metabolism. 2001; 50(6):667-673). A clinical study also showed a decrease in LDL (“bad”) cholesterol levels in diabetics taking vanadium supplements (J Clin Endocrinol Metab. 2001; 86(3):1410-1417). Long-term vanadium use has not been studied, so the use of vanadium by diabetics should be avoided. Vanadium overdose has been associated with depression and mania. Individuals with a history of mood disorders should not use vanadium supplements. Vanadium should never be taken in amounts greater than 1.8 mg/day. Side effects from vanadium may include nausea, stomach upset, vomiting, and diarrhea. High doses of vanadium can cause liver or kidney disease. Patients taking blood-thinning drugs such as Heparin should not use vanadium, as it can potentiate the blood thinning effects of these drugs.

Advantra-Z: Advantra-Z is a patented form of Synephrine, an alkaloid that is derived from Citrus aurantium. It is considered as a safe alternative to the now banned Ephedra and is believed to promote thermogenesis. Manufacturers claim that Synephrine provides the “fat burning” effects of Ephedra, but without side effects such as sleeplessness, jitters, elevated blood pressure, etc. There are studies, however, that indicate that Synephrine can elevate blood pressure and heart rate (e.g. Ann. Pharmacother. [2006] 40(1):53-7).

Garcinia cambogia: The active ingredient in Garcinia cambogia is hydroxycitric acid (HCA). This fruit is native to India and has been a part of the diet there for centuries. Numerous studies have concluded that HCA causes no adverse side effects and that the quantity and quality of scientific evidence is sufficient to support the safe, supplemental use of HCA at doses of up to 2,800 mg daily. There are no known medication interactions associated with the use of HCA. However, patients taking oral hypoglycemic agents are advised to use caution before using HCA, due to the possibility of exacerbating the action of hypoglycemic medications. Consult a physician before commencing use. Individuals diagnosed with Diabetes mellitus should use extreme caution in taking HCA/Garcinia cambogia due to its glycemic action. Individuals with Alzheimer’s disease or other dementia syndromes should also avoid using HCA. Pending additional research HCA is viewed as safe and non-toxic for most healthy adult individuals.

Green tea: Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Ginseng: Ginseng is any one of eleven distinct species of perennial plants with fleshy roots, belonging to the Panax genus in the family Araliaceae. Ginseng has traditionally been used as a restorative tonic to increase energy, stamina and well being. Researchers have found that ginseng may be effective in promoting weight loss and diabetes control. Side effects of Ginseng can include nausea, diarrhea, headaches, nose bleeds, high blood pressure, low blood pressure and breast pain. Ginseng may also lead to induction of mania in depressed patients who mix it with antidepressants.

Rhodiola rosea: This herb is included among a class of plant derivatives called adaptogens which differ from chemical stimulants, such as nicotine, and do not have the same physiological effects. Rhodiola may be effective at improving mood and alleviating depression. Pilot studies on human subjects have shown that it improves physical and mental performance, and reduces fatigue. However, there is no current clinical evidence that Rhodiola facilitates weight loss. Although much less frequent than other herbs, side effects of Rhodiola include irritability, restlessness and insomnia. Individuals suffering from psychological disorders such as bi-polar disorder should not take this herb. Rhodiola can cause mood swings and hallucinations. This could be very serious, depending how severe the bi-polar disorder is. Women who are pregnant should not take Rhodiola as it can cause anxiety in some women. This can have negative effects on the baby. People with allergies should also avoid this herb. If you are taking medications or other herbal products consult your doctor before taking Rhodiola.

Eleuthero: Eleutherococcus senticosus or Eleuthero is the plant commonly referred to as Siberian Ginseng. Eleuthero has been used as a therapeutic agent, credited with increasing the length and quality of life, preventing infections, improving memory and stimulating appetite. Individuals with medicated high blood pressure should consult their doctor before taking Eleuthero because it may reduce their need for medication. Eleuthero has been found to enhance the effectiveness of mycin class antibiotics.

Accuslim dosage

As a dietary supplement, take 1-3 tablets 30 minutes prior to each meal.

Accuslim conclusion

Like many diet pills on the market Accuslim has not been independently tested. Citrus aurantium in Accuslim is not a proven, safe or effective substitute for Ephedra. While Citrus aurantium may be safer than Ephedra, it has been shown to elevate blood pressure and body temperature and it is not advisable to take this compound long-term. Due to the high stimulant content Accuslim should not be taken without first taking medical advice.

Many of the ingredients in DecaTrim can also be found in another controversial diet pill, Lipofuze. The ingredients in weight loss supplements need to be present in potent enough concentrations to have a significant effect. As the amount of each ingredient in DecaTrim is not disclosed, it is difficult to assess if they present at the required levels to promote weight loss. The effects of potential interaction between the 10 ingredients in DecaTrim have not been clinically evaluated. Internet reviews indicate that some users have reported nausea, profuse sweating, headaches, insomnia and increased heart rate after taking DecaTrim.

Related article: DecaTrim Review

DecaTrim side effects

The ingredients in the DecaTrim formulation are not harmful in themselves. However, the potential effects of interaction between the 10 ingredients, has not been clinically evaluated. Internet reviews indicate that some users have reported headaches, insomnia, nausea, profuse sweating and increased heart rate.

DecaTrim pros

• Some of the ingredients have been evaluated in clinical trials and shown to be safe
• The official product website offers a money-back guarantee

DecaTrim cons

• The DecaTrim formulation does not contain any strong appetite suppressing ingredients
• Decatrim can have side effects
• DecaTrim is a propriety blend. Are there high enough doses of the active ingredients to get the job done?
• The official DecaTrim website has few testimonials
• No details of the manufacturer, the country where DecaTrim is made or a contact address are given on the website

DecaTrim ingredients

DecaTrim is fat burner which contains 6 patented and 4 clinically tested ingredients. The ingredients include:

ThermoDiamine: This ingredient is the patented form of evodiamine, a Chinese fruit that is claimed to burn fat by increasing the body’s production of heat and reducing its ability to store fat. However, no studies have been carried out in man so far. To there is no clinical data on whether or not Thermodiamine works in human subjects.

Razberi-K: Also known as raspberry ketone or 4-(4-hydroxyphenyl) butan-2-one, this ingredient is thought to enhance weight loss due to stimulation of norepinephrine. Razberi-K is said to aid fat oxidation, but studies on human beings have not convincingly proved its effectiveness. One study undertaken on rodents showed that raspberry ketones inhibited fat synthesis as well as a rise in blood triglycerides and overall, helped prevent excess weight gain. The chemical structure of raspberry ketone is similar to that of capsaicin and synephrine. Both of these compounds are can boost thermogenesis through the release of norepinephrine. However, there are health risks associated with these two ingredients; synephrine has been shown to have dangerous cardiovascular side effects, while capsaicin can cause gastrointestinal problems.  There are no documented side effects related to raspberry ketone consumption.

FucoPure: This is the patented version of fucoxanthin, a seaweed extract. There are a number of studies that have shown fucoxanthin’s ability to boost metabolism, but to date, they have all been carried out in pre-clinical studies. Additionally, it has been shown clinically that compounds like fucoxanthin have low bioavailability in man (see Br J Nutr. 2008;100(2):273-277). One gram of seaweed has several times the amount of iodine that most adults require on a daily basis. Therefore, a potential fucoxanthin side effect could include changes in thyroid function due to iodine excess.

ForsLean: ForsLean is extracted from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is claimed to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.

GuggulEZ100: This is a patented extract of Commiphora mukul. Other common names are Gugalipids and Guggul. Guggul lowers cholesterol and triglyceride levels and helps maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. A number of studies have investigated the anti-inflammatory potential of Guggul. Researchers concluded that Guggal was safe and highly effective in lowering the various lipid fractions that are known to contribute to coronary heart disease. There is some clinical evidence to suggest that Guggul may promote fat burning (see J Postgrad Med. 1995;41(1):5-7) by stimulating the secretion of thyroid T3 hormone.

Green tea: Green tea has been demonstrated to promote modest weight loss. However, it needs to be used in relatively high concentrations, and contain high levels of catechins. In DecaSlim, the amount of green tea present in the formulation is not indicated. Users sensitive to caffeine could experience any of the following side effects: restlessness, irritability, sleeping problems, tremors, heart palpitations, loss of appetite, upset stomach, nausea, frequent urination and skin rash.

Bioperine: This ingredient is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been proven in clinical studies to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements due to increased absorption.

Capsaicin: This compound is found in chile peppers. It is believed that capsaicin generates heat in the body thereby boosting the burning of calories. However, it appears that very high doses are required for it to be effective. Severe gastrointestinal side effects have been reported in patients ingesting capsaicin. While rare, serious allergic reactions to capsaicin can occur. Contact a physician immediately should difficulty breathing, skin rash, hives, swelling of the throat, lips, or face, severe dizziness, or itching be experienced.

Synephrine HCL: Synephrine is derived from the Citrus aurantium plant used for a variety of purposes in traditional Chinese medicine. Research indicates that it can act as an effective stimulant. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium induces a relatively modest increase in thermogenesis. Reported side effects include: increased heart rate and blood pressure, insomnia, nervousness, anxiety, tremor, dry mouth, blurred vision and headache. Synephrine may also reduce the ability to urinate. Consult a physician if you have any history of cardiac disease, high blood pressure, anxiety or urinary problems. Also, combining decongestants with other medicines with similar side effects may lead to dangerous complications.

7-OXO DHEA: This compound is a metabolite of DHEA, a steroid hormone. It has been shown to have a positive effect on thyroid hormone levels in obese people, without apparent side effects (J Nutr Biochem. 2007;18:629-634. Current Therapeutics. 2000;7:435-442). 7-OXO DHEA has been found to be safe in animals at high doses and in humans at up to 200 mg daily. 7-OXO-DHEA should not be taken if being treated with glucocorticoids, as it may interfere with their effectiveness.

Adapexin-P contains compounds that have been clinically proven to promote weight loss, although some can have side effects. The official website gives no indication of the country where Adapexin-P is manufactured or the quality control procedures. Additionally, at the time of writing there is no contact address or telephone number for the manufacturer on the website – always a cause for concern.

See also: Adapexin-P Review

Adapexin-P side effects

Adapexin-P contains relatively high amounts of caffeine which is a stimulant and diuretic that may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine. There are other ingredients in Adapexin-P that have side effects, as listed below.

Adapexin-P pros

• Many of Adapexin-P’ s ingredients have been assessed in clinical trials
• The official Adapexin-P website offers a money-back guarantee

Adapexin-P cons

• Adapexin-P can cause side effects
• The level of claimed weight loss achieved with Adapexin-P seems high and could be unhealthy
• No details of the manufacturer, the country where Adapexin-P is made, product quality control and purity or a contact address are given on the website – always a red flag

Adapexin-P ingredients

Phenylethylamine (37.5 mg): Also called L-Phenylalanine, is an alkaloid that functions as a neurotransmitter in the brain, and is believed to boost levels of dopamine. The increase in dopamine promotes a feeling of wellbeing. It is claimed to have appetite suppressing effects as well. Side effects of phenylalanine that are common but not serious include heartburn, nausea, constipation and mild headaches. Serious side effects associated with phenylalanine include insomnia, confusion, dizziness or intense headache. An individual experiencing these symptoms should consult with a physician before continuing phenylalanine doses. Severe side effects associated with phenylalanine include tightness or sharp pain in the chest, difficulty breathing and a sudden increase in heart rate or blood pressure. Symptoms of allergic reaction to phenylalanine include sudden rash or hives and swelling of the face, neck, lips or tongue. An individual experiencing these side effects should seek immediate emergency medical attention. Phenylalanine has the potential to adversely interact with antipsychotic medications prescribed to treat schizophrenia, depression and bipolar disorder such as thioridazine, clozapine and haloperidol. This may result in symptoms of tardive dyskinesia (involuntary movements of the limbs, facial muscles and tongue). Phenylalanine may also diminish the effectiveness of levodopa, a medication prescribed to ease the symptoms of Parkinson’s disease.

Glucomannan (1000mg): This is a soluble fiber supplement. Studies have shown that glucomannan can promote weight loss by absorbing dietary fats. Glucomannan can bind with and hinder the absorption of certain nutrients, meaning that it may adversely influence the effectiveness of the other ingredients in the Adapexin-P formulation.

Chromax™ (500mcg): Also known as chromium polynicotinate, this ingredient is a niacin-bound chromium complex that plays a key role in the regulation of insulin function, and the maintenance of healthy blood sugar and cholesterol levels. Chromium is involved in carbohydrate, protein and fat metabolism. The clinical studies that have been carried out on chromium have been inconclusive; some demonstrating that it had a subtle effect on weight loss and others showing that it was ineffective. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change, and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Ginger Root (50mg): Ginger (Zingiber officinale) contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Side effects associated with ginger are rare, but if taken in excessive doses the herb may cause mild heartburn, diarrhea and irritation of the mouth.

Vitamin B12 (500mcg): This vitamin plays an important role in the normal functioning of the brain and nervous system. Vitamin B12 is believed to be safe when used orally in amounts that do not exceed the recommended dietary allowance (RDA). The RDA for vitamin B12 in pregnant women is 2.6 µg per day and 2.8 µg during lactation periods. There is insufficient reliable information available about the safety of consuming greater amounts of vitamin B12 during pregnancy. Vitamin B12 supplements in theory should be avoided in people sensitive or allergic to cobalamin, cobalt, or any other product ingredients. However, direct allergy to a vitamin or nutrient is extremely rare.

Raspberry ketones (100mg): This ingredient, also known as razberi-K or 4-(4-hydroxyphenyl) butan-2-one, is believed to promote weight loss by stimulating norepinephrine. Razberi-K is claimed to aid fat oxidation, but clinical studies have not convincingly demonstrated its effectiveness. One study undertaken on rodents showed that raspberry ketones blocked fat synthesis as well as an increase in blood triglycerides and helped to prevent excess weight gain. The chemical structure of raspberry ketone is similar to that of capsaicin and synephrine. Both of these compounds have the ability to boost thermogenesis through the release of norepinephrine. However, there are health risks associated with the use of these two ingredients; synephrine has been demonstrated to have cardiovascular side effects, while capsaicin has been shown to cause gastrointestinal problems in many users. No side effects related to raspberry ketone consumption have been reported.

Evodiamine (50mg): Evodiamine has been used for hundreds of years in China as a weight loss supplement. Preliminary studies suggest that Evodiamine may increase body heat leading to enhanced calorie burning. It may also reduce fat uptake. There are no reported side effects at recommended doses.

Caffeine Anhydrous (199mg): This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, jitters, headaches, diarrhea, insomnia and increased heart rate.

Adapexin-P dosage

Two capsules are taken twice daily before meals. Each bottle of Adapexin-P lasts 30 days.

CliniSlim contains compounds that have been demonstrated clinically to promote weight loss. The official website gives no indication of the country where CliniSlim is manufactured or the quality control procedures. Additionally, at the time of writing there is no contact address or telephone number for the manufacturer on the website – always a cause for concern. Clinislim contains stimulants that may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine.

See also: CliniSlim Review

CliniSlim pros

• CliniSlim’s ingredients have been evaluated in clinical studies
• The official CliniSlim website offers a money-back guarantee

CliniSlim cons

• CliniSlim can cause side effects
• The level of achievable weight loss claimed for CliniSlim seems high and could be unhealthy
• No details of the manufacturer, the country where CliniSlim is made, product quality control and purity or a contact address are given on the website – always a cause for concern

Clinislim side effects

The manufacturer claims that out of all the clinical studies, there have been no reports of any adverse effects. However, it is important to stress that these studies were carried out on some of the individual ingredients, and not on CliniSlim itself. The manufacturer does not recommend CliniSlim for individuals sensitive to caffeine or other stimulants.

Clinislim contains guarana which is a stimulant and diuretic which may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine. Garcinia cambogia, another ingredient in CliniSlim, contains hydroxy citric acid (HCA). The FDA recently warned against taking supplements that contain HCA because of potential serious liver complications. A clinical study showed that 23 people experienced serious complications after taking HCA over a 7 year period. Until more studies are carried out on Garcinia cambogia and HCA, a doctor should be consulted before taking these compounds. Potential side effects are liver problems, jaundice, brown urine, light stools and upset stomach.

CliniSlim ingredients

There are seven primary active ingredients found in CliniSlim. These are chromium, Garcinia cambogia (suppresses appetite), glucomannan (suppresses appetite and absorbs dietary fat), guarana (boosts energy), yerba mate (enhances mood), damania leaf (slows down the digestion process), and Gymnema sylvestre (promotes fat burning).

The ingredients are grouped into 3 separate formulations:

• Guarana, yerba mate, and damiana
• Glucomannan
• Garcinia cambogia, Gymnema sylvestre, and chromium polynicotinate

Looking at the ingredients in greater detail:

Chromium (250mcg/serving): This ingredient plays an important role in the regulation of insulin function, and in the maintenance of healthy blood sugar and cholesterol levels. Chromium is involved in carbohydrate, protein and fat metabolism. The clinical studies that have been carried out on chromium have been inconclusive; some demonstrating that it had a subtle effect on weight loss and others showing that it was ineffective. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Damiana leaf (200 mg/serving): A herb which has been used as a general tonic for both men and women, particularly when hormone-related conditions are present. Damiana also has antidepressant, anti-anxiety, diuretic and mild laxative effects. It is relatively safe in regular doses, although the long term effects have not been evaluated. Damiana does have a traditional background as an abortive and therefore should not be taken during pregnancy. Damiana also has a mild hypoglycemic effect so individuals on diabetes medication, or those who suffer from hypoglycaemia, must use caution with this herb. Damiana may interfere with the body’s absorption of iron, so iron levels must be monitored while on this herb. The safety of Damiana in children has not been evaluated and it should not be used.

Garcinia cambogia (1500 mg/serving): Hydroxycitric acid (HCA), a compound in Garcinia cambogia, is claimed to suppress appetite and promote fat burning. The FDA recently warned against taking supplements that contain HCA because of potential serious liver complications. A clinical study showed that 23 people experienced serious complications after taking HCA over a 7 year period. Until more studies are carried out on Garcinia cambogia and HCA, a doctor should be consulted before taking these compounds. Potential side effects are liver problems, jaundice, brown urine, light stools and upset stomach.

Glucomannan (1000 mg/serving): This is a soluble fiber. Studies have shown that glucomannan can promote weight loss by absorbing dietary fats. Glucomannan can bind with and hinder the absorption of certain nutrients, meaning that it may adversely influence the effectiveness of the other ingredients in the CliniSlim formulation.

Guarana (750 mg/serving): Guarana is a common ingredient in many popular stimulant-based weight loss pills. It is included primarily for its caffeine content (caffeine is a thermogenic agent) but it also has anti-oxidant and diuretic properties. Guarana may cause side effects that can include: anxiety; diarrhea; headache; increased urination; nausea; nervousness; shakiness; tremors; trouble sleeping; upset stomach; and vomiting.

Gymnema sylvestre (75 mg/serving): This is a woody climbing plant native to tropical regions of India. Its bitter leaves can inhibit the ability to taste sugar, thereby reducing sugar cravings. Gymnema sylvestre has been used in Indian Ayurvedic medicine since the 6th century B.C. No side effects have been reported, but researchers have not established whether this herb is absolutely safe for pregnant women or during lactation.

Yerba Mate (4005 mg/serving): Yerba Mate (400 mg). A South American shrub that contains the xanthine alkaloids caffeine, theobromine and theophylline. Yerba mate has about half the caffeine content of coffee. Theobromine and theophylline are stimulants, although they have a less potent effect on the central nervous system (CNS) than caffeine. Flushing, nausea, vomiting, irritability, nervousness, increased urination and headache may occur with yerba mate. If any of these effects persist or worsen, contact your doctor promptly. Stronger but very infrequent side effects include stomach pain, yellowing eyes and skin, dark urine, fever, muscle twitching and unusually fast/slow/irregular heartbeat.

CliniSlim dosage

There are a total of 300 capsules in each bottle. A bottle lasts 30 days. The manufacturer recommends taking 10 capsules per day. CliniSlim is taken 30 minutes prior to breakfast and lunch.

CliniSlim conclusion

CliniSlim is a stimulant heavy pill containing guarana and yerbe mate, both of which contain high amounts of caffeine. The FDA recently warned against taking supplements that contain hydroxycitric acid, a compound in Garcinia cambogia, because of potential serious liver complications. In addition, no details of the manufacturer, the country where CliniSlim is made, product quality control and purity, or a contact address are given on the website – always a cause for concern.

Thermodrenix, manufactured by Blackstone Nutrition, contains 3 patented weight loss ingredients. There is no indication of the country where Thermodrenix is manufactured or the quality control procedures. Thermodrenix contains caffeine. In some individuals, stimulants like this can cause side effects such as restlessness, headaches, jitteriness, nervousness, irritability, insomnia, palpitations, elevated heartbeat and increased blood pressure.

See also: Thermodrenix Review

Thermodrenix pros

• The manufacturer of Thermodrenix gives the complete list of ingredients and the amounts present
• Thermodrenix has a money-back guarantee
• Thermodrenix contains optimal concentrations of ingredients
• Some of Thermodrenix’s ingredients have been assessed in clinical trials and are believed to be safe

Thermodrenix cons

• No information is available on the manufacturer, Blackstone Health Sciences
• Thermodrenix is not a registered trademark – a cause for concern
• No details of the manufacturer, the country where Adipozin is made, product quality control and purity or a contact address are given on the website – always a red flag

Thermodrenix dosage

The manufacturer recommends that 4 capsules of Thermodrenix are taken daily. Each bottle of Thermodrenix contains 60 capsules or 15 days supply.

Thermodrenix ingredients

Thermodrenix’s ingredients include:

SuperCitrimax (1400 mg): Super Citrimax has been demonstrated clinically to reduce appetite, burn fat and lower blood cholesterol levels. The active ingredient, hydroxycitric acid (HCA) is derived from the rind of the Garcinia cambogia fruit. A review of 14 studies indicated that HCA and Super Citrimax caused no adverse side effects at doses of up to 2,800 mg daily [4,667 mg of Super Citrimax]. There are no known drug interactions associated with the use of HCA. However, patients taking oral hypoglycemic agents are advised to use caution before taking HCA, due to the possibility of amplifying the action of hypoglycemic medications. Individuals diagnosed with Diabetes mellitus should use extreme caution in taking HCA/Garcinia cambogia due to its glycemic action. Individuals with Alzheimer’s disease or other dementia syndromes should also avoid using HCA. Consult a physician before commencing use.

Green tea (1000 mg): There is some evidence that green tea offers weight loss benefits. Most studies have indicated that it is one essential catechin, epigallocatechin gallate (EGCG), working in combination with caffeine that provides the weight loss benefits. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Forslean (250 mg): This compound is derived from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is understood to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.

Gymnema Sylvestre extract (200 mg): This is a woody climbing plant native to tropical regions of India. Its bitter leaves can eliminate the ability to taste sugar, thereby reducing cravings for sugar. Gymnema sylvestre has been used in Indian Ayurvedic medicine since the 6th century B.C. No side effects have been reported, but researchers have not established whether this herb is absolutely safe for pregnant women or during lactation.

Bioperine (5 mg): Bioperine is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been shown in clinical research to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption, even if true, may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements or drugs due to increased absorption. No significant Bioperine side effects have been reported at this time. Minor gastrointestinal discomfort or GI symptoms may occur with high doses of Bioperine.

Thermodrenix conclusion

The manufacturer of Thermodrenix provides a complete list of ingredients and their quantities. SuperCitrimax is a useful, but not particularly powerful weight loss ingredient, but it is present at the correct concentration. Green tea and caffeine are also present in potent doses. Gymnema and Forslean do not add much to this formulation. Thermodrenix is a caffeine heavy diet pill. If sensitive to stimulants, this is a weight loss product should be used with caution.