Many of the ingredients in LipoFuze can also be found in another controversial diet pill, Apidexin. The medicinal herbs and other natural ingredients that are typically found in weight loss products need to be present in a potent enough dosage to have any effect. As the proportion of each ingredient in LipoFuze is not disclosed, it is difficult to assess if they present in the required dosages to promote significant weight loss.
The effects of potential interaction between the 14 ingredients in LipoFuze have not been clinically evaluated. Internet reviews indicate that some users have reported headaches, nausea, insomnia, profuse sweating and increased heart rate after taking LipoFuze.
Related article: LipoFuze
LipoFuze ingredients
Lipofuze is fat burner which contains 6 patented and 4 clinically tested ingredients. The ingredients include:
ThermoDiamine: This ingredient is the patented form of evodiamine, a Chinese fruit that is claimed to burn fat by increasing the body’s production of heat and reducing the body’s ability to store fat. But no studies have been conducted in man so far. To date only an animal-based study has been carried out and there is no clinical data on whether or not evodiamine works in human subjects.
Razberi-K: Also known as raspberry ketone or 4-(4-hydroxyphenyl) butan-2-one, this ingredient is thought to enhance weight loss via the stimulation of norepinephrine. Razberi-K is said to aid fat oxidation, but studies on human beings have not convincingly proved its effectiveness. One study performed on rodents demonstrated that raspberry ketones prevented fat synthesis as well as the rise of blood triglycerides and overall, helped prevent excess weight gain. The chemical structure of raspberry ketone is similar to that of capsaicin and synephrine. Both of these compounds are well documented for their ability to boost thermogenesis through the release of norepinephrine. However, there are health risks with these two ingredients; synephrine has been shown to have dangerous cardiovascular side effects, while capsaicin has been demonstrated to cause gastrointestinal problems in many users. There are no documented side effects related to raspberry ketone consumption.
FucoPure: This is the patented version of fucoxanthin, a seaweed extract. There are a number of studies that demonstrate fucoxanthin’s ability to boost metabolism, but to date, they have all been carried out in pre-clinical studies on animals. It is also proven that, this ingredient cannot be absorbed by human body easily. Additionally, it has been shown clinically that compounds like fucoxanthin have low bioavailability in man (see Br J Nutr. 2008 Aug;100(2):273-7). One gram of seaweed has several times the amount of iodine that most adults require on a daily basis. Therefore, a potential fucoxanthin side effect could include changes in thyroid function due to iodine excess.
ForsLean: ForsLean is derived from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is understood to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.
GuggulEZ100: This is a patented extract of Commiphora mukul. Other common names are Gugalipids and Guggul. In India Guggul is used widely for the reduction of blood cholesterol. Guggul lowers cholesterol and triglyceride levels and helps maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. A number of studies have investigated the anti-inflammatory potential of Guggul. Researchers concluded that Guggal was safe and highly effective in lowering the various lipid fractions that are known to contribute to coronary heart disease. There is some clinical evidence to suggest that Guggul may promote fat burning (see J Postgrad Med. 1995 Jan-Mar;41(1):5-7) by stimulating the secretion of thyroid T3 hormone.
Green tea: Green tea has been shown to promote some weight loss. However, it needs to be used in relatively high concentration, and contain high levels of catechins. In Lipofuze, the amount of green tea present in the formulation is not indicated. Users sensitive to caffeine could experience any of the following side effects: restlessness, irritability, sleeping problems, tremors, heart palpitations, loss of appetite, upset stomach, nausea, frequent urination and skin rash.
Bioperine: This ingredient is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been shown in clinical research to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption, even if true, may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements due to increased absorption.
Capsaicin: This compound is found in chile peppers. It is believed that capsaicin generates heat in the body thereby boosting the burning of calories. However, it appears that very high doses are required for it to be effective. Severe gastrointestinal side effects have been reported in patients ingesting capsaicin. While rare, serious allergic reactions to capsaicin can occur. Contact a physician immediately should difficulty breathing, skin rash, hives, swelling of the throat, lips, or face, severe dizziness, or itching be experienced.
Synephrine HCL: Synephrine is derived from the Citrus aurantium plant used for a variety of purposes in traditional Chinese medicine. Research indicates that it can act as an effective stimulant. After Ephedra was banned by the F.D.A., diet pill makers sought to discover an equivalent. They thought they had found it with Synephrine and, while Synephrine is effective, there is no research that points to Ephedra and Synephrine being comparable. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium induces a relatively modest increase in thermogenesis. Reported side effects include: increased heart rate and blood pressure, insomnia, nervousness, anxiety, tremor, dry mouth, blurred vision, and headache. Synephrine may also reduce the ability to urinate. Consult a physician if you have any history of cardiac disease, high blood pressure, anxiety, or urinary problems. Also, combining decongestants with other medicines with similar side effects may lead to dangerous complications.
7-OXO DHEA: This compound is a metabolite of DHEA, a steroid hormone. This ingredient has been shown to have a positive effect on thyroid hormone levels in obese people, without apparent side effects (see J Nutr Biochem. 2007; 18(9):629-34. Current Therapeutics, (7):435-442 2000). 7-OXO DHEA has been found to be safe in animals at high doses and in humans at up to 200 mg daily. 7-OXO-DHEA should not be taken if you are being treated with glucocorticoids, as it may interfere with their effectiveness.
Other ingredients in the LipoFuze formulation include cinnamon, phenylethylamine, ginger, and 20-hydroxyecdysone (a plant steroid considered to have anabolic activity in mammals).
Is Lipofuze effective?
User feedback on Lipofuze has varied. Some have reported fast weight loss in the first few days (water loss?) when combined with diet and exercise, but the rate of weight loss is lower than claimed by the manufacturers.
28 comments ↓
I tried the detox first and didn’t work, not a pound lost. I have lost 4 pounds in a week using lipofuze. I drink one in the morning and one before lunch with a full glass of water and have felt no side effects, just a bit of heartburn for a few minutes, I burp and it goes away. I’m still hopeful I will loose more pounds. I’ll let you know in a month.
I agree with Valerie. Im on my last day of the detox and it hasnt done anything. I started the diet pills yesterday and had heartburn and I had a hard time getting to sleep. The main problem I had was…..after teh 2nd pill I splurged and had icecream and was extremely nauseas for 3-4 hours afterwards. My advice is if you are going to start this diet DO NOT SPLURGE. I am resting from it today and will start again tomorrow. Other than those 2 items I had no side effects.
I have to say that I’ve been using Lipofuze for over a month now, but I am also eating healthier and watching what I eat, although I don’t have that much time for exercising, but everyone has noticed that I have lost weight, and even the scale has noticed.
Anyways, I haven’t experienced any side effects yet, if you follow the rule that you have to eat 30 minutes after you take the pill, I think that the pill is safe to take.
I took detox for the 3 days. I didnt exercise or change my eating habits & lost 3.5 lbs. Today, i started the regular pill & breakfast was fine. I took another pill at lunch & have having some side effects. I feel jittery, I have a bit of a headache, strong and rapid heart rate & feel as though my pupils are very dialted. Has anyone else experienced this & kept using this pill?
I took lipofuze and had terrible side effects, strong and rapid heart rate, anxious feelings, jitters, excessive sweating and no weight lost. After having looked more closely at the some of these ingredients and their risk factors, I will no longer take lipofuze, the risks are simply not worth it.
I took a capsule and had a terrible reaction – sweating, fast heart beat and I lost consciousness. Thank goodness my friends were around when it happened and took good care of me until I regained my sense of awareness. I had terrible headaches for about three weeks after taking only one capsule.
I have been taking it for weeks and havent lost much..sending it back for a refund..
I took lipofuze for 3 days…. I have had extreme dizziness, vomiting, headaches, irritability, and trouble sleeping. Simply NOT worth taking with the amount of side effects.
I took it for 3 days & had violent vomiting & horrible stomach cramps. I also had dizziness. Definitely not worth all this, as I won’t be able to function.
first day i have a bad headache. i wonder if it works
First pill make me feel that I going to pass out. Too much headache, fast heartbeat, detection of several irrigular heartbeat, stomach upset, and I couldn’t sleep for the whole night. I will not recomended to anyone.
just ordered a bottle, gonna try it a see what happens… i hope i lose this weight, thats all i want!! kinda excited…
Hi I was almost done with a bottles worth ya it worked great but i just had to go into the ER monday night and couldn’t figure out why I took another one today and figured that lipofuze was the reason… i can’t understand why it didn’t happen in the beginning but it just started so I’m done with this not worth the heart problems i’ll just stick to exercising and hope this doesn’t happen to anyone else…. pills can’t do nothin only you and the gym… yes i’m gonna try to get my money back i can’t believe this is what caused it I will be contacting them ASAP
I have been using lipofuze for 4 days and last night on my way home from work it gave me such a massive headache my vision was blurred. By time I got home I was nauseous and the sound of my own breathing made my head hurt even worse.
1st day. first pill no effects. by the time lunch came round hadstomach pain, i thought it was because i was hungry. took second pill, had chicken salad for lunch and have been with an upset stomach for the past 2 hours. We will see what happens!
Hey Guys thanks for the comments. I guess I’ll pass- I love internet message boards. Thanks again.
I took the three day detox and nothing. I am on my third day with the pills and yesterday and today I feel gurgling in my tummy and today I have had a headache and felt nauseated…Tummy bug or side effects?
So is the concensus NOT to try this pill? If you don’t mind my asking those who had negative effects – is the weight you’re trying to lose more than 20 lbs or are you all in moderately good health?
I started the pills yesterday and today I have headache but that is it. Hoping that will be all but we will see. I did not take the detox pills. I am trying to loose 50+ pounds so I have to figure out if side effects are worth it.
I am on my second day of the pills. I did the detox first and it did nothing. I take the first pill in the morning and then eat breakfast. I dont have any side effects then, just a little heartburn maybe. At lunch time when i take the second pill i get a little light headed and sick to my stomach. Eating doesnt seem to help much. I dont think that its really anything i cant live with though. I suppose your body has to get used to it. I guess if i didnt feel any different i would assume its not working. We will see…I will keep everyone updated on the results. Im weighing in at 150 to begin and anxious to see results hopefully!
I am trying to lose some baby fat, maybe about 40 lb after all these comments. I am little hesitant in taking it . Does everyone experience the same side effects of headache nausea, fast heart rate and upset stomach. I just purchase the product, and I wish I saw these comments before I make a purchase.
I am on my first full week of using the pill. The first 3 days of using it, I had headaches, sweating (and it’s super hot in Tennessee), a few jitters, and a little bit of nausea. I’m on day number 7 and Im better now. I have lost 3 pounds so far and will continue to try it for the rest of the month. For me, the side effects are not unbareable, just a little bothersome. I will continue to see what happens and report back in a month. I can definately tell that the pill is working when I go potty. I hope my appearence and scale say the same thing soon! I plan to start excerising today and will continue with it. It all depends on if you want to continue with the pill after the side effects subside…. your choice. See you guys in a month.
This is my 4th day on Lipofuze. I have lost a couple pounds(I think..i have a really crappy scale that never shows the same number). The side effects I’ve noticed are sweats(normal…the pill has thermo ingredients that raise the body temperature, thats normal and an intended effect to help weight loss). And I have a sick feeling in my stomach…not really nausea, just a heavy feeling in my guts. The main side effect that I’m concerned with is that I’m really irregular now…for the first couple days…i didn’t poop, then I pooped a small amount on the 2nd night that was really tough to get out. And since then, it was a small amount yesterday morning, and a small amount today, both of which really loose stools. Sorry i know this is gross but I don’t understand how I’m supposed to lose weight if my body isn’t getting rid of what I’m eating. Concerned…can anyone give me pointers.
Oh yea I am noticing that the sick feeling is getting less every day, I think it’s just my body adjusting to the increased metabolism.
Hmmm, I really want to lose about 15 pounds. Most of these side effects seem bearable, but I’m a freak when it comes to pills. I hope that the worst I get is nausea.
Also, I am only 17, but I’ll be 18 in December. Would it be risky for me to use them?
I just bought the pills too…the side effects don’t scare me as much as my weight gain…I think maybe some of the side effects could be from the diet change in lives too…I need to lose 20 lbs and so here I go!
8-13
My first day….I feel a bit warm and I have a little bit of a weird feeling with light…and my eyes…
a bit excited…yet scared but lets continue!
ok…so I took my second pill and man do I want to throw up…not sure if my body is just getting adjusted or what. I guess I will give it a day or two and if no change I think I will stop taking them…. to be continued!
It’s my third day, i have taken my sixth pill. Side effects – heart burn and no sleep. I haven’t checked my weight.
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