Hi Tech Pharmaceuticals Lipodrene SR is a stimulant based fat burning diet pill manufactured by a company of suspect credibility. The medicinal herbs and other ingredients that are typically found in weight loss products need to be present in a potent enough dosage to have any effect. As the proportion of each ingredient in Hi Tech Pharmaceuticals Lipodrene SR is not disclosed, it is difficult to assess if they present in the required dosages to promote significant weight loss. Hi Tech Pharmaceuticals Lipodrene SR contains stimulants and can have side effects.

Lipodrene SR side effects

Side effects reported for Lipodrene SR include headache, nausea, nervousness, jitters, racing heart and dizziness.

Lipodrene SR pros

• There are positive testimonials with regard to weight loss using Lipodrene SR

Lipodrene SR cons

• Lipodrene SR is a propriety blend. Are there high enough doses of the active ingredients to get the job done?
• The official product website has no testimonials
• Lipodrene SR is not supported with a money back guarantee
• Lipodrene SR contains stimulants and side effects have been reported

Lipodrene SR dosage

There are 90 Lipodrene SR tablets in each container. The manufacturer recommends taking 3 tablets daily.

Lipodrene SR ingredients

The Lipodrene SR ingredients include:

Citrus aurantium (standardized for synephrine): Citrus aurantium is a fruit known as Zhi Shi in traditional Chinese medicine and as bitter orange in other countries. It contains synephrine, a compound that is structurally related to Ephedrine, as well as Octopamine and Tyramine. Synephrine has been claimed to increase metabolic rate and fat breakdown, but this is not supported by clinical data which indicated no significant effect on weight loss (Am J Cardiol. 2004;94:1359-1361). It also acts as a mild appetite suppressant and an energy booster. The effects of Synephrine are enhanced when it is combined with caffeine.

Coleus forskholii: This is an herb that has been demonstrated to enhance lipolysis. It may also inhibit fat storage. Another way that Coleus forskholii may promote fat loss is by stimulating thyroid hormone (thyroxin) production. Thyroxin controls metabolism and can enhance metabolic rate, promoting fat loss. In an 8 week clinical study subjects taking Coleus forskholii lost on average 9.9 lbs of body weight compared to the placebo group where only 1.1 lbs of fat was lost. Another study (J Internat Soc Sports Nutr. 2005;2(2):54-62, 2005) concluded that Coleus forskohlii did not appear to promote weight loss but that it may help mitigate weight gain in overweight females with no clinically significant side effects. The dose of Coleus forskohlii used in this study was 500 mg daily (10% CF extract).

Commiphora mukul: This ingredient is the standardized extract of a resin of a tree native to India. Another common name for this compound is Guggul. In India Guggul is used to help lower blood cholesterol and triglyceride levels. It can help maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. A clinical study found that Guggul can boost fat burning (see J Postgrad Med. 1995; 41(1): 5-7) by stimulating the secretion of the T3 thyroid hormone.

Coryphantha macromeris extract: This is a cactus, and although there do not appear to be any clinical studies supporting its effectiveness as a fat burner, it is a known stimulant.

Green tea: Most studies have demonstrated that it is one essential catechin, epigallocatechin gallate (EGCG), working in combination with caffeine that provides the modest weight loss benefits of green tea. Green tea may also slow the increase in blood sugar following a meal. It does this by inhibiting the action of a digestive enzyme amylase. This enzyme is responsible for the breakdown of carbohydrates, which can cause blood sugar levels to increase following a meal. Green tea has been reported to promote weight loss by increasing the metabolic rate, boosting calorie burn (e.g. American Journal of Clinical Nutrition 2005; 81(1): 122-129).

Hoodia gordonii: Both animal and human studies indicate that Hoodia gordonii can function as an appetite suppressant if used appropriately. The hypothalamus, which is located in the midbrain, has nerve cells that detect glucose. When food is consumed blood glucose levels increase, and the hypothalamus is activated, informing the brain that the stomach is full. The P57 molecule contained in Hoodia is about 10,000 times more effective than glucose in stimulating these nerve cells. The overall effect is to fool the brain into thinking that the stomach is full, thus suppressing the appetite. However, genuine certified Hoodia gordonii is now in short supply. Hi Tech Pharmaceuticals provide no evidence that their Hoodia is genuine.

Naringin: A citrus flavanoid commonly found in grapefruit. Studies reveal that naringin can inhibit some digestive enzymes which can affect the metabolism and breakdown of drugs. There is also some evidence that the effects and levels of caffeine can be extended when consumed with naringin.

Phenylethylamine (PEA): An alkaloid that functions as a neurotransmitter in the brain, and is believed to boost levels of dopamine. The increase in dopamine promotes a feeling of wellbeing. It is claimed to have appetite suppressing effects as well. However, phenylethylamine is rapidly metabolised by the enzyme monamine oxidase, and thus very little orally consumed PEA actually enters into the bloodstream.

Yohimbe: This is a tree bark containing a variety of pharmacologically active chemicals and is often used as an aphrodisiac. A number of studies support Yohimbe’s positive effect on weight loss (e.g. Isr J Med SCI 1991. 27(10):550-6). However, its effects are not dramatic. Serious side effects associated with products containing Yohimbe have been reported to the FDA, including renal failure, seizures and death. The major alkaloid in Yohimbe is Yohimbine, a chemical that induces vasodilation, thereby lowering blood pressure. Yohimbine is also used as a prescription drug in the United States. Additional side effects may include central nervous system stimulation that causes anxiety attacks.

5-hydroxytryptophan: 5-HTP is often used to treat mild depression due to it being a precursor to serotonin (a chemical neurotransmitter found in the brain). There is some evidence 5-HTP may promote weight loss (Am J Clin Nutr. 1992;56:863-867; J Neural Transm. 1989;76:109-117), but only when taken in large doses (one study used 900 mg per day). Since 5-HTP is part of 275 mg blend, it is not present in an optimal dosage in the Lipodrene SR formulation.

Lipodrene SR conclusion

There is nothing paticularly new or exclusive in the Lipodrene SR formulation. The ingredients can be found in many other diet pills. The weight loss claims made for Lipodrene SR are not backed up by clinical trial data. There are no clear-cut quantities of the ingredients contained in the Lipodrene SR formulation listed on the bottle. It is therefore impossible to evaluate if there are enough of any of the ingredients to be effective as a weight loss supplement at the recommended daily dose. At the time of writing, Hi-Tech Pharmaceuticals, the manufacturers of Lipodrene SR are currently being indicted for a “generic pill fraud scheme”. According to US government investigators, Hi-Tech Pharmaceuticals manufactured generic versions of drugs (such as steroids as well as Viagra, Vioxx, Cialis, Ambien, Valium, Xanax and others) and sold them via the Internet, violating several U.S. laws.

Lipodrene SR contact details

Address: Hi-Tech Pharmaceuticals, 6015-B Unity Drive Norcross, GA 30071, USA

Website: http://hitechpharma.com/products/fl_lipodrene.htm

Tel: 1.888.855.7919