The manufacturer of Lipofuze claims that this diet pill can deliver a weight loss of 10 pounds of fat in 7 days. To lose 1.5 pounds of fat a day ,the body needs to burn approximately 5000 calories above normal calorie usage. This represents a tripling in calorie burn. LipoFuze claims to do this by accelerating metabolism – but is it possible to triple metabolic rate using a pill? “No”, is the simple answer.
Many of the ingredients in LipoFuze can also be found in another controversial diet pill, Apidexin. The medicinal herbs and other natural ingredients that are typically found in weight loss products need to be present in potent enough dosages to have any effect. As the proportion of each ingredient in LipoFuze is not disclosed, it is difficult to assess if they are present in the required dosages to promote significant weight loss.
Lipofuze side effects
The ingredients in the LipoFuze formulation are not harmful in themselves. However, the effect of interaction between the 14 ingredients has not been clinically evaluated. Internet reviews indicate that some users have reported headaches, nausea, insomnia, profuse sweating and increased heart rate.
Is Lipofuze effective?
User feedback on Lipofuze has varied. Some have reported fast weight loss in the first few days (water loss?) when combined with diet and exercise, but the rate of weight loss is lower than claimed by the manufacturers.
Pros
- Some of the ingredients have been tested in clinical trials and are believed to be safe
- The company does not endorse automatic enrollment programs
- The official product website offers a money-back guarantee
Cons
- LipoFuze is relatively expensive for one month’s supply
- The formulation does not contain any strong appetite suppressing ingredients like Hoodia or Caralluma
- LipoFuze is a propriety blend. Are there high enough doses of the active ingredients to get the job done?
- The official product website has few testimonials
- No details of the manufacturer, the country where LipoFuze is made or a contact address are given on the website – a red flag
LipoFuze ingredients
Lipofuze is fat burner which contains 6 patented and 4 clinically tested ingredients. The ingredients include:
ThermoDiamine: This ingredient is the patented form of evodiamine, a Chinese fruit that is claimed to burn fat by increasing the body’s production of heat and reducing the body’s ability to store fat. But no studies have been conducted in man so far. To date only an animal-based study has been carried out and there is no clinical data on whether or not evodiamine works in human subjects.
Razberi-K: Also known as raspberry ketone, this ingredient is thought to enhance weight loss via the stimulation of norepinephrine. Razberi-K is said to aid fat oxidation, but studies on human beings have not convincingly proved its effectiveness. One study performed on rodents demonstrated that raspberry ketones prevented fat synthesis as well as the rise of blood triglycerides and overall, helped prevent excess weight gain.
FucoPure: This is the patented version of fucoxanthin, a seaweed extract. There are a number of studies that demonstrate fucoxanthin’s ability to boost metabolism, but to date, they have all been carried out in pre-clinical studies on animals. It is also proven that, this ingredient cannot be absorbed by human body easily. Additionally, it has been shown clinically that compounds like fucoxanthin have low bioavailability in man (see Br J Nutr. 2008; 100 (2): 273-277).
ForsLean: ForsLean is derived from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is understood to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and decrease in blood pressure.
GuggulEZ100: This is a patented extract of Commiphora mukul. Other common names are Gugalipids and Guggul. In India Guggul is used widely for the reduction of blood cholesterol. Guggul lowers cholesterol and triglyceride levels and helps maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. A number of studies have investigated the anti-inflammatory potential of Guggul. Researchers concluded that Guggal was safe and highly effective in lowering the various lipid fractions that are known to contribute to coronary heart disease. There is some clinical evidence to suggest that Guggul may promote fat burning (see J Postgrad Med. 1995; 41(1): 5-7) by stimulating the secretion of thyroid T3 hormone.
Green tea: Green tea has been shown to promote some weight loss. However, it needs to be used in relatively high concentration, and contain high levels of catechins. In Lipofuze, the amount of green tea present in the formulation is not indicated.
Bioperine: This ingredient is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been shown in clinical research to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption, even if true, may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements due to increased absorption.
Capsaicin: This compound is found in chile peppers. It is believed that capsaicin generates heat in the body thereby boosting the burning of calories. However, it appears that very high doses are required for it to be effective.
Synephrine HCL: Synephrine is derived from the Citrus aurantium plant used for a variety of purposes in traditional Chinese medicine. Research indicates that it can act as an effective stimulant. After Ephedra was banned by the F.D.A., diet pill makers sought to discover an equivalent. They thought they had found it with Synephrine and, while Synephrine is effective, there is no research that points to Ephedra and Synephrine being comparable. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium a relatively modest icrease in thermogenesis.
7-OXO DHEA: This compound is a metabolite of DHEA, a steroid hormone. This ingredient has been shown to have a positive effect on thyroid hormone levels in obese people, without apparent side effects (see J Nutr Biochem. 2007; 18: 629-634. Current Therapeutics. 200; 7: 435-442).
Other ingredients in the LipoFuze formulation include cinnamon, phenylethylamine, ginger, and 20-hydroxyecdysone (a plant steroid considered to have anabolic activity in mammals).
Conclusion
The manufacturers of LipoFuze are open about its composition, so that it is possible to research the ingredients beyond the information provided on the website. However, there are no clear-cut quantities of the ingredients contained in this formula listed on the bottle. It is therefore impossible to evaluate if there are enough of any of the ingredients to be effective as a weight loss supplement at the recommended daily dose.
Manufacturers’ contact details
There is no manufacturer’s contact address for LipoFuze.
LipoFuze email address: customerservice@lipofuze.com
LipoFuze telephone number: 1-887-641-9564
