Many of the ingredients in DecaTrim can also be found in another controversial diet pill, Lipofuze. The ingredients in weight loss supplements need to be present in potent enough concentrations to have a significant effect. As the amount of each ingredient in DecaTrim is not disclosed, it is difficult to assess if they present at the required levels to promote weight loss. The effects of potential interaction between the 10 ingredients in DecaTrim have not been clinically evaluated. Internet reviews indicate that some users have reported nausea, profuse sweating, headaches, insomnia and increased heart rate after taking DecaTrim.

Related article: DecaTrim Review

DecaTrim side effects

The ingredients in the DecaTrim formulation are not harmful in themselves. However, the potential effects of interaction between the 10 ingredients, has not been clinically evaluated. Internet reviews indicate that some users have reported headaches, insomnia, nausea, profuse sweating and increased heart rate.

DecaTrim pros

• Some of the ingredients have been evaluated in clinical trials and shown to be safe
• The official product website offers a money-back guarantee

DecaTrim cons

• The DecaTrim formulation does not contain any strong appetite suppressing ingredients
• Decatrim can have side effects
• DecaTrim is a propriety blend. Are there high enough doses of the active ingredients to get the job done?
• The official DecaTrim website has few testimonials
• No details of the manufacturer, the country where DecaTrim is made or a contact address are given on the website

DecaTrim ingredients

DecaTrim is fat burner which contains 6 patented and 4 clinically tested ingredients. The ingredients include:

ThermoDiamine: This ingredient is the patented form of evodiamine, a Chinese fruit that is claimed to burn fat by increasing the body’s production of heat and reducing its ability to store fat. However, no studies have been carried out in man so far. To there is no clinical data on whether or not Thermodiamine works in human subjects.

Razberi-K: Also known as raspberry ketone or 4-(4-hydroxyphenyl) butan-2-one, this ingredient is thought to enhance weight loss due to stimulation of norepinephrine. Razberi-K is said to aid fat oxidation, but studies on human beings have not convincingly proved its effectiveness. One study undertaken on rodents showed that raspberry ketones inhibited fat synthesis as well as a rise in blood triglycerides and overall, helped prevent excess weight gain. The chemical structure of raspberry ketone is similar to that of capsaicin and synephrine. Both of these compounds are can boost thermogenesis through the release of norepinephrine. However, there are health risks associated with these two ingredients; synephrine has been shown to have dangerous cardiovascular side effects, while capsaicin can cause gastrointestinal problems.  There are no documented side effects related to raspberry ketone consumption.

FucoPure: This is the patented version of fucoxanthin, a seaweed extract. There are a number of studies that have shown fucoxanthin’s ability to boost metabolism, but to date, they have all been carried out in pre-clinical studies. Additionally, it has been shown clinically that compounds like fucoxanthin have low bioavailability in man (see Br J Nutr. 2008;100(2):273-277). One gram of seaweed has several times the amount of iodine that most adults require on a daily basis. Therefore, a potential fucoxanthin side effect could include changes in thyroid function due to iodine excess.

ForsLean: ForsLean is extracted from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is claimed to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.

GuggulEZ100: This is a patented extract of Commiphora mukul. Other common names are Gugalipids and Guggul. Guggul lowers cholesterol and triglyceride levels and helps maintain a healthy balance of HDL, the good cholesterol, relative to LDL, the bad cholesterol (the HDL/LDL ratio), thereby protecting against cardiovascular disease and atherosclerosis. A number of studies have investigated the anti-inflammatory potential of Guggul. Researchers concluded that Guggal was safe and highly effective in lowering the various lipid fractions that are known to contribute to coronary heart disease. There is some clinical evidence to suggest that Guggul may promote fat burning (see J Postgrad Med. 1995;41(1):5-7) by stimulating the secretion of thyroid T3 hormone.

Green tea: Green tea has been demonstrated to promote modest weight loss. However, it needs to be used in relatively high concentrations, and contain high levels of catechins. In DecaSlim, the amount of green tea present in the formulation is not indicated. Users sensitive to caffeine could experience any of the following side effects: restlessness, irritability, sleeping problems, tremors, heart palpitations, loss of appetite, upset stomach, nausea, frequent urination and skin rash.

Bioperine: This ingredient is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been proven in clinical studies to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements due to increased absorption.

Capsaicin: This compound is found in chile peppers. It is believed that capsaicin generates heat in the body thereby boosting the burning of calories. However, it appears that very high doses are required for it to be effective. Severe gastrointestinal side effects have been reported in patients ingesting capsaicin. While rare, serious allergic reactions to capsaicin can occur. Contact a physician immediately should difficulty breathing, skin rash, hives, swelling of the throat, lips, or face, severe dizziness, or itching be experienced.

Synephrine HCL: Synephrine is derived from the Citrus aurantium plant used for a variety of purposes in traditional Chinese medicine. Research indicates that it can act as an effective stimulant. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium induces a relatively modest increase in thermogenesis. Reported side effects include: increased heart rate and blood pressure, insomnia, nervousness, anxiety, tremor, dry mouth, blurred vision and headache. Synephrine may also reduce the ability to urinate. Consult a physician if you have any history of cardiac disease, high blood pressure, anxiety or urinary problems. Also, combining decongestants with other medicines with similar side effects may lead to dangerous complications.

7-OXO DHEA: This compound is a metabolite of DHEA, a steroid hormone. It has been shown to have a positive effect on thyroid hormone levels in obese people, without apparent side effects (J Nutr Biochem. 2007;18:629-634. Current Therapeutics. 2000;7:435-442). 7-OXO DHEA has been found to be safe in animals at high doses and in humans at up to 200 mg daily. 7-OXO-DHEA should not be taken if being treated with glucocorticoids, as it may interfere with their effectiveness.

Adapexin-P contains compounds that have been clinically proven to promote weight loss, although some can have side effects. The official website gives no indication of the country where Adapexin-P is manufactured or the quality control procedures. Additionally, at the time of writing there is no contact address or telephone number for the manufacturer on the website – always a cause for concern.

See also: Adapexin-P Review

Adapexin-P side effects

Adapexin-P contains relatively high amounts of caffeine which is a stimulant and diuretic that may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine. There are other ingredients in Adapexin-P that have side effects, as listed below.

Adapexin-P pros

• Many of Adapexin-P’ s ingredients have been assessed in clinical trials
• The official Adapexin-P website offers a money-back guarantee

Adapexin-P cons

• Adapexin-P can cause side effects
• The level of claimed weight loss achieved with Adapexin-P seems high and could be unhealthy
• No details of the manufacturer, the country where Adapexin-P is made, product quality control and purity or a contact address are given on the website – always a red flag

Adapexin-P ingredients

Phenylethylamine (37.5 mg): Also called L-Phenylalanine, is an alkaloid that functions as a neurotransmitter in the brain, and is believed to boost levels of dopamine. The increase in dopamine promotes a feeling of wellbeing. It is claimed to have appetite suppressing effects as well. Side effects of phenylalanine that are common but not serious include heartburn, nausea, constipation and mild headaches. Serious side effects associated with phenylalanine include insomnia, confusion, dizziness or intense headache. An individual experiencing these symptoms should consult with a physician before continuing phenylalanine doses. Severe side effects associated with phenylalanine include tightness or sharp pain in the chest, difficulty breathing and a sudden increase in heart rate or blood pressure. Symptoms of allergic reaction to phenylalanine include sudden rash or hives and swelling of the face, neck, lips or tongue. An individual experiencing these side effects should seek immediate emergency medical attention. Phenylalanine has the potential to adversely interact with antipsychotic medications prescribed to treat schizophrenia, depression and bipolar disorder such as thioridazine, clozapine and haloperidol. This may result in symptoms of tardive dyskinesia (involuntary movements of the limbs, facial muscles and tongue). Phenylalanine may also diminish the effectiveness of levodopa, a medication prescribed to ease the symptoms of Parkinson’s disease.

Glucomannan (1000mg): This is a soluble fiber supplement. Studies have shown that glucomannan can promote weight loss by absorbing dietary fats. Glucomannan can bind with and hinder the absorption of certain nutrients, meaning that it may adversely influence the effectiveness of the other ingredients in the Adapexin-P formulation.

Chromax™ (500mcg): Also known as chromium polynicotinate, this ingredient is a niacin-bound chromium complex that plays a key role in the regulation of insulin function, and the maintenance of healthy blood sugar and cholesterol levels. Chromium is involved in carbohydrate, protein and fat metabolism. The clinical studies that have been carried out on chromium have been inconclusive; some demonstrating that it had a subtle effect on weight loss and others showing that it was ineffective. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change, and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Ginger Root (50mg): Ginger (Zingiber officinale) contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Side effects associated with ginger are rare, but if taken in excessive doses the herb may cause mild heartburn, diarrhea and irritation of the mouth.

Vitamin B12 (500mcg): This vitamin plays an important role in the normal functioning of the brain and nervous system. Vitamin B12 is believed to be safe when used orally in amounts that do not exceed the recommended dietary allowance (RDA). The RDA for vitamin B12 in pregnant women is 2.6 µg per day and 2.8 µg during lactation periods. There is insufficient reliable information available about the safety of consuming greater amounts of vitamin B12 during pregnancy. Vitamin B12 supplements in theory should be avoided in people sensitive or allergic to cobalamin, cobalt, or any other product ingredients. However, direct allergy to a vitamin or nutrient is extremely rare.

Raspberry ketones (100mg): This ingredient, also known as razberi-K or 4-(4-hydroxyphenyl) butan-2-one, is believed to promote weight loss by stimulating norepinephrine. Razberi-K is claimed to aid fat oxidation, but clinical studies have not convincingly demonstrated its effectiveness. One study undertaken on rodents showed that raspberry ketones blocked fat synthesis as well as an increase in blood triglycerides and helped to prevent excess weight gain. The chemical structure of raspberry ketone is similar to that of capsaicin and synephrine. Both of these compounds have the ability to boost thermogenesis through the release of norepinephrine. However, there are health risks associated with the use of these two ingredients; synephrine has been demonstrated to have cardiovascular side effects, while capsaicin has been shown to cause gastrointestinal problems in many users. No side effects related to raspberry ketone consumption have been reported.

Evodiamine (50mg): Evodiamine has been used for hundreds of years in China as a weight loss supplement. Preliminary studies suggest that Evodiamine may increase body heat leading to enhanced calorie burning. It may also reduce fat uptake. There are no reported side effects at recommended doses.

Caffeine Anhydrous (199mg): This compound is incorporated into many weight loss supplements available today. Caffeine can cause anxiety, jitters, headaches, diarrhea, insomnia and increased heart rate.

Adapexin-P dosage

Two capsules are taken twice daily before meals. Each bottle of Adapexin-P lasts 30 days.

CliniSlim contains compounds that have been demonstrated clinically to promote weight loss. The official website gives no indication of the country where CliniSlim is manufactured or the quality control procedures. Additionally, at the time of writing there is no contact address or telephone number for the manufacturer on the website – always a cause for concern. Clinislim contains stimulants that may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine.

See also: CliniSlim Review

CliniSlim pros

• CliniSlim’s ingredients have been evaluated in clinical studies
• The official CliniSlim website offers a money-back guarantee

CliniSlim cons

• CliniSlim can cause side effects
• The level of achievable weight loss claimed for CliniSlim seems high and could be unhealthy
• No details of the manufacturer, the country where CliniSlim is made, product quality control and purity or a contact address are given on the website – always a cause for concern

Clinislim side effects

The manufacturer claims that out of all the clinical studies, there have been no reports of any adverse effects. However, it is important to stress that these studies were carried out on some of the individual ingredients, and not on CliniSlim itself. The manufacturer does not recommend CliniSlim for individuals sensitive to caffeine or other stimulants.

Clinislim contains guarana which is a stimulant and diuretic which may cause anxiety, diarrhea, increased urination, headaches, insomnia and upset stomach, particularly in individuals sensitive to caffeine. Garcinia cambogia, another ingredient in CliniSlim, contains hydroxy citric acid (HCA). The FDA recently warned against taking supplements that contain HCA because of potential serious liver complications. A clinical study showed that 23 people experienced serious complications after taking HCA over a 7 year period. Until more studies are carried out on Garcinia cambogia and HCA, a doctor should be consulted before taking these compounds. Potential side effects are liver problems, jaundice, brown urine, light stools and upset stomach.

CliniSlim ingredients

There are seven primary active ingredients found in CliniSlim. These are chromium, Garcinia cambogia (suppresses appetite), glucomannan (suppresses appetite and absorbs dietary fat), guarana (boosts energy), yerba mate (enhances mood), damania leaf (slows down the digestion process), and Gymnema sylvestre (promotes fat burning).

The ingredients are grouped into 3 separate formulations:

• Guarana, yerba mate, and damiana
• Glucomannan
• Garcinia cambogia, Gymnema sylvestre, and chromium polynicotinate

Looking at the ingredients in greater detail:

Chromium (250mcg/serving): This ingredient plays an important role in the regulation of insulin function, and in the maintenance of healthy blood sugar and cholesterol levels. Chromium is involved in carbohydrate, protein and fat metabolism. The clinical studies that have been carried out on chromium have been inconclusive; some demonstrating that it had a subtle effect on weight loss and others showing that it was ineffective. Chromium has reported side effects, even when taken in low doses of 200-400 mcg per day. These side effects include headaches, insomnia and sleep disturbances. Irritability, mood change and some weight gain may also occur. There have been cognitive, perceptual and motor dysfunction reported in some extreme cases. A high dose of chromium, 600-2400 mcg per day, may cause anemia, thrombocytopenia, hemolysis, hepatic dysfunction and renal failure.

Damiana leaf (200 mg/serving): A herb which has been used as a general tonic for both men and women, particularly when hormone-related conditions are present. Damiana also has antidepressant, anti-anxiety, diuretic and mild laxative effects. It is relatively safe in regular doses, although the long term effects have not been evaluated. Damiana does have a traditional background as an abortive and therefore should not be taken during pregnancy. Damiana also has a mild hypoglycemic effect so individuals on diabetes medication, or those who suffer from hypoglycaemia, must use caution with this herb. Damiana may interfere with the body’s absorption of iron, so iron levels must be monitored while on this herb. The safety of Damiana in children has not been evaluated and it should not be used.

Garcinia cambogia (1500 mg/serving): Hydroxycitric acid (HCA), a compound in Garcinia cambogia, is claimed to suppress appetite and promote fat burning. The FDA recently warned against taking supplements that contain HCA because of potential serious liver complications. A clinical study showed that 23 people experienced serious complications after taking HCA over a 7 year period. Until more studies are carried out on Garcinia cambogia and HCA, a doctor should be consulted before taking these compounds. Potential side effects are liver problems, jaundice, brown urine, light stools and upset stomach.

Glucomannan (1000 mg/serving): This is a soluble fiber. Studies have shown that glucomannan can promote weight loss by absorbing dietary fats. Glucomannan can bind with and hinder the absorption of certain nutrients, meaning that it may adversely influence the effectiveness of the other ingredients in the CliniSlim formulation.

Guarana (750 mg/serving): Guarana is a common ingredient in many popular stimulant-based weight loss pills. It is included primarily for its caffeine content (caffeine is a thermogenic agent) but it also has anti-oxidant and diuretic properties. Guarana may cause side effects that can include: anxiety; diarrhea; headache; increased urination; nausea; nervousness; shakiness; tremors; trouble sleeping; upset stomach; and vomiting.

Gymnema sylvestre (75 mg/serving): This is a woody climbing plant native to tropical regions of India. Its bitter leaves can inhibit the ability to taste sugar, thereby reducing sugar cravings. Gymnema sylvestre has been used in Indian Ayurvedic medicine since the 6th century B.C. No side effects have been reported, but researchers have not established whether this herb is absolutely safe for pregnant women or during lactation.

Yerba Mate (4005 mg/serving): Yerba Mate (400 mg). A South American shrub that contains the xanthine alkaloids caffeine, theobromine and theophylline. Yerba mate has about half the caffeine content of coffee. Theobromine and theophylline are stimulants, although they have a less potent effect on the central nervous system (CNS) than caffeine. Flushing, nausea, vomiting, irritability, nervousness, increased urination and headache may occur with yerba mate. If any of these effects persist or worsen, contact your doctor promptly. Stronger but very infrequent side effects include stomach pain, yellowing eyes and skin, dark urine, fever, muscle twitching and unusually fast/slow/irregular heartbeat.

CliniSlim dosage

There are a total of 300 capsules in each bottle. A bottle lasts 30 days. The manufacturer recommends taking 10 capsules per day. CliniSlim is taken 30 minutes prior to breakfast and lunch.

CliniSlim conclusion

CliniSlim is a stimulant heavy pill containing guarana and yerbe mate, both of which contain high amounts of caffeine. The FDA recently warned against taking supplements that contain hydroxycitric acid, a compound in Garcinia cambogia, because of potential serious liver complications. In addition, no details of the manufacturer, the country where CliniSlim is made, product quality control and purity, or a contact address are given on the website – always a cause for concern.

Thermodrenix, manufactured by Blackstone Nutrition, contains 3 patented weight loss ingredients. There is no indication of the country where Thermodrenix is manufactured or the quality control procedures. Thermodrenix contains caffeine. In some individuals, stimulants like this can cause side effects such as restlessness, headaches, jitteriness, nervousness, irritability, insomnia, palpitations, elevated heartbeat and increased blood pressure.

See also: Thermodrenix Review

Thermodrenix pros

• The manufacturer of Thermodrenix gives the complete list of ingredients and the amounts present
• Thermodrenix has a money-back guarantee
• Thermodrenix contains optimal concentrations of ingredients
• Some of Thermodrenix’s ingredients have been assessed in clinical trials and are believed to be safe

Thermodrenix cons

• No information is available on the manufacturer, Blackstone Health Sciences
• Thermodrenix is not a registered trademark – a cause for concern
• No details of the manufacturer, the country where Adipozin is made, product quality control and purity or a contact address are given on the website – always a red flag

Thermodrenix dosage

The manufacturer recommends that 4 capsules of Thermodrenix are taken daily. Each bottle of Thermodrenix contains 60 capsules or 15 days supply.

Thermodrenix ingredients

Thermodrenix’s ingredients include:

SuperCitrimax (1400 mg): Super Citrimax has been demonstrated clinically to reduce appetite, burn fat and lower blood cholesterol levels. The active ingredient, hydroxycitric acid (HCA) is derived from the rind of the Garcinia cambogia fruit. A review of 14 studies indicated that HCA and Super Citrimax caused no adverse side effects at doses of up to 2,800 mg daily [4,667 mg of Super Citrimax]. There are no known drug interactions associated with the use of HCA. However, patients taking oral hypoglycemic agents are advised to use caution before taking HCA, due to the possibility of amplifying the action of hypoglycemic medications. Individuals diagnosed with Diabetes mellitus should use extreme caution in taking HCA/Garcinia cambogia due to its glycemic action. Individuals with Alzheimer’s disease or other dementia syndromes should also avoid using HCA. Consult a physician before commencing use.

Green tea (1000 mg): There is some evidence that green tea offers weight loss benefits. Most studies have indicated that it is one essential catechin, epigallocatechin gallate (EGCG), working in combination with caffeine that provides the weight loss benefits. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Forslean (250 mg): This compound is derived from the root of Coleaus forskohlii, which is native to warm temperate habitats including India, and is the only known plant source of the natural compound Forskolin. Amongst other effects, this compound is understood to increase lean body mass and help optimize body composition though cAMP (cyclic adenosine monophosphate) activation. A number (but not all) of clinical studies have indicated that Coleaus forskohlii may cause an increase in heart rate and a decrease in blood pressure.

Gymnema Sylvestre extract (200 mg): This is a woody climbing plant native to tropical regions of India. Its bitter leaves can eliminate the ability to taste sugar, thereby reducing cravings for sugar. Gymnema sylvestre has been used in Indian Ayurvedic medicine since the 6th century B.C. No side effects have been reported, but researchers have not established whether this herb is absolutely safe for pregnant women or during lactation.

Bioperine (5 mg): Bioperine is a standardized extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper). It contains 95 percent Piperine. Bioperine has been shown in clinical research to increase the absorption of ingredients in nutritional supplement formulations. Additional absorption, even if true, may or may not necessarily be beneficial. It is possible that the use of Bioperine may increase the side effects of certain supplements or drugs due to increased absorption. No significant Bioperine side effects have been reported at this time. Minor gastrointestinal discomfort or GI symptoms may occur with high doses of Bioperine.

Thermodrenix conclusion

The manufacturer of Thermodrenix provides a complete list of ingredients and their quantities. SuperCitrimax is a useful, but not particularly powerful weight loss ingredient, but it is present at the correct concentration. Green tea and caffeine are also present in potent doses. Gymnema and Forslean do not add much to this formulation. Thermodrenix is a caffeine heavy diet pill. If sensitive to stimulants, this is a weight loss product should be used with caution.

Xyphedrex is a fat burning and energy boosting formulation offering 4 major ingredients. Unfortunately, there is no meaningful clinical data supporting the product posted on the official website. Xyphedrex is a stimulant heavy pill and side effects can include headaches, jitteriness, nervousness, irritability, insomnia and elevated heartbeat.

Related article: Xyphedrex Review

Xyphedrex pros

• Xyphedrex comes with a money-back guarantee

Xyphedrex cons

• Xyphedrex reviews are mixed with some users reporting no positive results with regard to weight loss
• Xyphedrex is a stimulant heavy diet pill
• Xyphedrex contains high levels of caffeine
• Some users report experiencing side effects using Xyphedrex
• No details are provided on where Xyphedrex is manufactured or the quality control procedures involved

Xyphedrex ingredients

Xyphedrex ‘s ingredients are:

• Dicaffeine malate
• Synephrine
• Chocamine
• Phenylethylamine
• Gelatin
• Magnesium stearate

Looking at the ingredients in greater detail:

Dicaffeine malate (200 mg): Originally used by the Coca Cola Company as an alternative to cocaine, DiCaffeine Malate is a stimulant-based ingredient used in soft drinks, energy drinks and dietary supplements. DiCaffeine Malate combines natural caffeine with Malic Acid. The combination forms an ionic bonded compound which is gentle on the stomach and is claimed to optimize energy, stimulate thermogenesis and increase mental focus. Many clinical studies have validated caffeine as an agent for boosting energy and helping with weight loss. However, there is no research supporting the fact that dicaffeine malate is any more effective than standard caffeine. DiCaffeine Malate may cause jitters, insomnia, headaches, increased heart rate and raised blood pressure.

Chocamine (200 mg): A proprietary extract of the cocoa plant. It contains numerous constituents including methylxanthines (theobromine, caffeine, and theophylline), biogenic amines (phenylethylamine and tyramine) amino acids (phenylalanine, tryptophan, tyrosine, others), minerals, numerous beneficial antioxidants, and possibly some non-psychoactive cannabanoid-related compounds. Chocamine produces a very smooth energy boost with no crash. This ingredient is not new to fat burners but does not actually promote weight loss. Chocamine contains caffeine, which can cause side effects (see above).

Phenylethylamine (20 mg): An alkaloid that functions as a neurotransmitter in the brain, and is believed to boost levels of dopamine. The increase in dopamine promotes a feeling of wellbeing. It is claimed to have appetite suppressing effects as well. Side effects of phenylalanine that are common but not serious include heartburn, nausea, constipation and mild headaches. Serious side effects associated with phenylalanine include insomnia, confusion, dizziness or intense headache. An individual experiencing these symptoms should consult with a physician before continuing phenylalanine doses. Severe side effects associated with phenylalanine include tightness or sharp pain in the chest, difficulty breathing and a sudden increase in heart rate or blood pressure. Symptoms of allergic reaction to phenylalanine include sudden rash or hives and swelling of the face, neck, lips or tongue. An individual experiencing these side effects should seek immediate emergency medical attention. Phenylalanine has the potential to adversely interact with antipsychotic medications prescribed to treat schizophrenia, depression and bipolar disorder such as thioridazine, clozapine and haloperidol. This may result in symptoms of tardive dyskinesia (involuntary movements of the limbs, facial muscles and tongue). Phenylalanine may also diminish the effectiveness of levodopa, a medication prescribed to ease the symptoms of Parkinson’s disease.

Synephrine HCL (20 mg): Synephrine is sourced from the Citrus aurantium plant. It can help promote fat burning, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium stimulates a relatively small increase in thermogenesis. Reported side effects of Synephrine include dry mouth, headache, nervousness, anxiety, insomnia, tremor, blurred vision, increased heart rate and blood pressure. Synephrine may also reduce the ability to urinate. It is advisable to consult a doctor if you have any history of high blood pressure, anxiety, urinary problems or cardiac disease. In addition, combining decongestants such as Synephrine with other medicines with similar side effects may lead to dangerous complications.

Xyphedrex dosage

A single bottle of Xyphedrex contains 60 capsules. The manufacturer recommends taking a single capsule 30 minutes before both breakfast and lunch. When used as directed, each bottle will last 1 month.

Xyphedrex conclusion

Although Xyphedrex does not contain ephedra, it is a stimulant heavy diet pill. If sensitive to stimulants, this is a weight loss product is best avoided.

MetaboSpeed XXX, a diet pill marketed by Lab88, contains high levels of the stimulants Guarana and Bitter Orange. Side effects that may occur from taking MetaboSpeed XXX include constipation, dehydration, muscle cramps, nausea, stomach discomfort, restlessness, jitters, nervousness, irritability, insomnia, rapid heartbeat and high blood pressure. MetaboSpeed XXX has not been evaluated in clinical studies and there are few testimonials supporting it effectiveness as a weight loss product.

See also: MetaboSpeed Review

MetaboSpeed XXX side effects

Side effects that may occur from taking MetaboSpeed XXX include constipation, dehydration, muscle cramps, nausea, stomach discomfort, restlessness, jitters, nervousness, irritability, insomnia, rapid heartbeat and high blood pressure. MetaboSpeed XXX may interact with both prescription and over-the-counter drugs. The stimulants in MetaboSpeed XXX, namely Guarana extract, Green tea extract, Bitter Orange extract and Korean Ginseng, can cause over-stimulation of the circulatory system. This may counteract the effectiveness of drugs used to lower blood pressure. If suffering from hypertension consult a doctor before taking MetaboSpeed XXX. While using MetaboSpeed XXX it is advisable to limit the consumption of any food or beverages that contain caffeine. Do not take MetaboSpeed XXX if suffering from diabetes, high blood pressure, renal disease, spasms, migraines, hyperthyroidism, heart disease, psychiatric disorders, or are allergic to chocolate or tyramine. Do not combine MetaboSpeed XXX with asthma medications. Take advice from a doctor first, if taking monoamine oxidase inhibitors (MAOIs).

MetaboSpeed XXX pros

• Some of MetaboSpeed XXX ingredients have been evaluated in clinical trials
• Details of the manufacturer, the country where MetaboSpeed XXX is made, product quality control and purity and a contact address are given on the website

MetaboSpeed XXX cons

• The MetaboSpeed XXX formulation is stimulant heavy
• There are side effects associated with MetaboSpeed XXX
• A significant component of the MetaboSpeed XXX formulation is a propriety blend. Are there high enough doses of the active ingredients for optimal weight loss effectiveness?

MetaboSpeed XXX ingredients

The ingredients in MetaboSpeed XXX are:

Guarana extract (800 mg): Guarana seeds contain five times more caffeine (caffeine is a thermogenic agent) than coffee beans. MetaboSpeed XXX has 800mg of Guarana extract standardized to 20% caffeine. In other words it contains 160mg of caffeine. Guarana is a popular ingredient in many stimulant-based weight loss pills. Guarana may cause side effects that can include: anxiety; diarrhea; headache; increased urination; nausea; nervousness; shakiness; tremors; trouble sleeping; upset stomach; and vomiting.

Bitter Orange extract (200 mg): This ingredient is an oil that is extracted from the Citrus aurantium fruit and is used for a variety of purposes in traditional Chinese medicine. It is a common ingredient in many diet pills. Bitter orange extract contains Synephrine, which is similar to ephedrine in that it raises blood pressure, heart rate and metabolism. Synephrine can help burn fat, suppress appetite and increase energy. However, clinical studies have revealed that Citrus aurantium induces a relatively modest increase in thermogenesis. Reported side effects include: increased heart rate and blood pressure, insomnia, nervousness, anxiety, tremor, dry mouth, blurred vision and headache. Synephrine may also reduce the ability to urinate. The adverse side effects of bitter orange can be exacerbated when used in combination with other stimulants such as caffeine, coffee, cola nut, Ephedra and Guarana. Consult a physician if you have any history of cardiac disease, high blood pressure, anxiety or urinary problems. Another potential problem with Citrus aurantium is that it could interact with a wide range of prescription drugs. Citrus aurantium inhibits an enzyme in the small intestine, known as CYP3A4, which can alter the metabolism of drugs and amplifying their activity. This enzyme is responsible for the metabolic activity of 50% of all prescription drugs.

Proprietary blend (160 mg): This low dose blend contains Green Tea, Vanadium, Garcinia cambogia, Ginseng, Bee Pollen and White Willow Bark.

Green tea: Green tea has been shown to promote modest weight loss. However, it needs to be taken in relatively high concentration, and to contain high levels of catechins. Users of green tea sensitive to caffeine could experience any of the following side effects: irritability, restlessness, nausea, insomnia, tremors, heart palpitations, upset stomach, frequent urination and skin rash.

Garcinia cambogia (standardized for hydroxycitric acid): Hydroxycitric acid (HCA), extracted from Garcinia cambogia, is claimed to suppress appetite and promote fat burning. Numerous studies have concluded that HCA causes no adverse side effects and that the quantity and quality of scientific evidence is sufficient to support the safe, supplemental use of HCA at doses of up to 2,800 mg daily. There are no known medication interactions associated with the use of HCA. However, patients taking oral hypoglycemic agents are advised to use caution before using HCA, due to the possibility of exacerbating the action of hypoglycemic medications. Consult a physician before commencing use. Individuals diagnosed with Diabetes mellitus should use extreme caution in taking HCA/Garcinia cambogia due to its glycemic action. Individuals with Alzheimer’s disease or other dementia syndromes should also avoid using HCA. Pending additional research HCA is viewed as safe and non-toxic for most healthy adult individuals.

Vanadium functions as an insulin mimic and has been shown to inhibit the synthesis of cholesterol. Although the use of high doses of vanadium supplements remains controversial, there are studies that suggest positive benefits in using vanadium to treat certain health conditions. For example, insulin sensitivity has been shown to improve in animals and human subjects treated with vanadium, suggesting that vanadium may be useful in helping to lower blood sugar levels in diabetics (e.g. Mol Cell Biochem. 2001; 218(1-2):93-96; Metabolism. 2001; 50(6):667-673). A clinical study has also shown a decrease in LDL (“bad”) cholesterol levels in diabetics taking vanadium supplements (J Clin Endocrinol Metab. 2001; 86(3):1410-1417). Long-term Vanadium use has not been studied, so the use of vanadium by diabetics should be avoided. Vanadium overdose has been associated with depression and mania. Individuals with a history of mood disorders should not use Vanadium supplements. Vanadium should never be taken in amounts greater than 1.8 mg/day. Side effects from Vanadium may include nausea, stomach upset, vomiting and diarrhea. High doses of vanadium can cause liver or kidney disease. Patients taking blood-thinning drugs such as Heparin should not use Vanadium, as it can potentiate the blood thinning effects of these drugs.

Metabo Speed XXX also contains phosphates which in one study, when combined with Garcinia cambogia, l-tyrosine and guggulsterones, promoted moderate weight loss. Unfortunately, neither l-tyrosine nor guggulsterones are present in the MetaboSpeed XXX formulation.

MetaboSpeed XXX dosage

Each bottle contains 60 pills or one months supply. Two pills are taken daily.